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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cytochrome P450 1B1
Summary
- UniProt ID
- Q16678
- Gene Symbol
-
- CYP1B1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q16678
- PubChem
- Q16678
- SwissLipids
- The Human Metabolome Database
- HMDBP01547
- The O-GlcNAc Database
- Q16678
Annotation
- Keyword
-
- 3D-structure
- Disease variant
- Fatty acid metabolism
- Glaucoma
- Heme
- Lyase
- Membrane
- Microsome
- Mitochondrion
- Monooxygenase
- Peters anomaly
- Reference proteome
- Steroid metabolism
- Gene Ontology (GO)
| GO Term |
|---|
| intracellular membrane-bounded organelle |
| mitochondrion |
| endoplasmic reticulum membrane |
Sequence
MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRRRQLRSAPPGPFAWPLIGNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSAEKKAAGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFISILAHQCDFRANPNEPAKMNFSYGLTIKPKSFKVNVTLRESMELLDSAVQNLQAKETCQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective CYP1B1 causes Glaucoma | Homo sapiens |
| Endogenous sterols | Homo sapiens |
| Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) | Homo sapiens |
| Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14557 | primary pulmonary hypertension | |
| DOID:14686 | Axenfeld-Rieger syndrome | |
| DOID:1570 | ectropion | |
| DOID:1596 | depressive disorder | |
| DOID:1612 | breast cancer | |
| DOID:1614 | male breast cancer | |
| DOID:162 | cancer | |
| DOID:1686 | glaucoma | |
| DOID:1727 | retinal vein occlusion | |
| DOID:9119 | acute myeloid leukemia |
