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Diacylglycerol kinase delta

Summary

UniProt ID

Q16760

Gene Symbol

DGKD
KIAA0145

Organism

Homo sapiens (human)

External Links

GlyGen

Q16760

PubChem

Q16760

SwissLipids

SLP:000000939

The Human Metabolome Database

HMDBP00234

The O-GlcNAc Database

Q16760

O-GlcNAcAtlas

Q16760

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell membrane
Coated pit
Cytoplasm
Endocytosis
Kinase
Lipid metabolism
Phosphoprotein
Protein transport
Reference proteome
Repeat
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

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GO Term
lipid phosphorylation
phosphatidic acid biosynthetic process
protein kinase C-activating G protein-coupled receptor signaling pathway
diacylglycerol metabolic process
negative regulation of protein kinase C signaling
endocytosis
signal transduction
protein transport
platelet activation
intracellular signal transduction

Displaying **all 6** entries
GO Term
nucleus
cytoplasm
plasma membrane
clathrin-coated pit
cytoplasmic vesicle
cytosol

Displaying **all 8** entries
GO Term
ATP-dependent diacylglycerol kinase activity
ATP binding
metal ion binding
kinase binding
diacylglycerol binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity

Annotation information from UniProt.

Sequence

MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
81	G49108TO	GlyGen The O-GlcNAc Database
87	G49108TO	GlyGen The O-GlcNAc Database
681	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Effects of PIP2 hydrolysis	Homo sapiens

Human Protein Atlas

ENSG00000077044

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Displaying entries **1 - 10** of 17 in total

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DO ID	Disease Name	Source
DOID:0050561	Lennox-Gastaut syndrome	DisGeNET DisGeNET
DOID:0060891	Parkinson's disease 19A	DisGeNET
DOID:0060895	Parkinson's disease 4	DisGeNET
DOID:0060896	Parkinson's disease 23	DisGeNET
DOID:1067	open-angle glaucoma	DisGeNET
DOID:1070	primary open angle glaucoma	DisGeNET
DOID:10933	obsessive-compulsive disorder	DisGeNET
DOID:11832	visual epilepsy	DisGeNET
DOID:14330	Parkinson's disease	DisGeNET
DOID:162	cancer	DisGeNET DisGeNET

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements