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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cystic fibrosis transmembrane conductance regulator
Summary
- UniProt ID
- Q1LX78
- Gene Symbol
-
- cftr
- Organism
- Danio rerio (zebrafish)
External Links
- PubChem
- Q1LX78
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Cell membrane
- Chloride channel
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Isomerase
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum membrane |
| cytosol |
| apical plasma membrane |
| plasma membrane |
| membrane |
| early endosome membrane |
| chloride channel complex |
| recycling endosome membrane |
Sequence
MQRSPVEDANCLSRYFFWWTNPIMRKGFKEKLRPSDVYQAPSQDAADILAERLEKEWDREVASGKKKPSLLRAMARCYIKPFLLFGFLLYIGEATKTVQPQLLGRIIASFDPAHEPERANGYFLAFGLGLLFTARFLLLQPAMFGLHHLGMQIRIALFSIIYKKTLKLSSRVLDKISTGQLVSLMSANLGKFDQSLGMAHFIWISPLQCILCTGLIWELIDVNSFCALAAISLLGVLQAFLSHKMGPYKAQKVLLTNKRLALTSEIMENLHSVKAYGWEEIMETLIKNIRQDEVKLTRKIGSLRYFYSSAYFFSAIFVIVAAVVPHALSRGINLRRIFTTLSYCMVLRMTVTRQLPGSIQMWYDTMRLIWKIEEFLSKEEYKLMEYDLSITELELQDVTASWDEGPGELLERIKQENKANGHHNGDAGLFFTNLYVAPVLKDISLKLKKGEMLAVTGSMGSGKSSLLMTILGELVPSSGKIRHSGRISYSSQTAWIMPGTIRDNILFGLTYDEYRYKSVVKACQLEEDLAALPEKDKTPMAEGGLNLSGGQKARVALARAVYRDADLYLLDAPFTHLDIATEKEIFDKCLCKLMASKTRILVTNKIEHLKRADKILLLHNGESFFYGTFPELQSERPDFSSLLLGLEAYDNISAERRCSILTETLHRVSVDESAGMQPERSAFRQVPPTKPMYIDERKASVIVNPLGVARKASFIQVPEEEVRRTLPDRKFSLVPENELVDESFMGSDVYHNHGVHMAGQRRQSVLAFMTNAQGQGRREHLQSSFRRRLSVVPQSELASELDIYTRRLSDSTYDMTGILEEENIEACLTDEIDEIEETFETTKWNTYVRYVSNNKSLLYVLIFILFIAAIEIAGSVAGIFLITDELWREEHQRSEPNMTKHSNASSSGQTYAITVTPTSSYYILYIYVATSESLLAMGFFRGLPFVHTTITISKKLHQKMLHAVLSAPMSVLNTMKTGRIMNRFTKDMATIDDMLPLLMFDFVQLTVVVVGCILVVSIVRPYIFLAATPLAIIFIVMRKYFLRTGQQLKQLETEARSPIFSHLIMSLKGLWTIRAFERQAYFEALFHKTLNTHTATWFLYLSTLRWFLFRADILFVFFFTLAAWIAVGTNQDKPGEIGIIICLAMLILGTFQWCVATSIAVDGMMRSVDRVFKFIDLPSETPKPDKGKDSDLIIENVDAQADSSWPHRGQIEVRNLTVKYTEAGHAVLKNLSFSAEGRQRVGILGRTGSGKSSLFNALLKLVYTDGEISIDGVNWNKMPLQKWRKAFGVVPQKVFIFTGPLRMNLDPYGCHSDEELWRVAEEVGLKTVIEQFPDKLDFQLEYGGYVLSNGHKQLICLARSILSGARILLLDEPSAHLDPVTIKVLKKTLRQSFSTCTILLSEHKVEPLLECQSFLMMDKGQVKTYDSIQKLLNETSHLKQAISPAERLKLFPRRNSSMRTPQSKLSSVTQTLQEEAEDNIQDTRL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ABC-family proteins mediated transport | Danio rerio |
| Aggrephagy | Danio rerio |
| RHO GTPases regulate CFTR trafficking | Danio rerio |
| RHOQ GTPase cycle | Danio rerio |
