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Beta-hexosaminidase A
Summary
- UniProt ID
- Q22492
- Gene Symbol
-
- hex-1
- Organism
- Caenorhabditis elegans
External Links
- GlycoProtDB
- GPDB0000786
- PubChem
- Q22492
- The O-GlcNAc Database
- Q22492
Annotation
- Keyword
-
- Glycoprotein
- Glycosidase
- Lysosome
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| ganglioside catabolic process |
| carbohydrate metabolic process |
| glycosaminoglycan metabolic process |
| GO Term |
|---|
| beta-N-acetylglucosaminidase activity |
| beta-N-acetylhexosaminidase activity |
| hexosaminidase activity |
| N-acetyl-beta-D-galactosaminidase activity |
Sequence
MRLLIPILIFALITTAVTWFYGRDDPDRWSVGGVWPLPKKIVYGSKNRTITYDKIGIDLGDKKDCDILLSMADNYMNKWLFPFPVEMKTGGTEDFIITVTVKDECPSGPPVHGASEEYLLRVSLTEAVINAQTVWGALRAMESLSHLVFYDHKSQEYQIRTVEIFDKPRFPVRGIMIDSSRHFLSVNVIKRQLEIMSMNKLNVLHWHLVDSESFPYTSVKFPELHGVGAYSPRHVYSREDIADVIAFARLRGIRVIPEFDLPGHTSSWRGRKGFLTECFDEKGVETFLPNLVDPMNEANFDFISEFLEEVTETFPDQFLHLGGDEVSDYIVECWERNKKIRKFMEEKGFGNDTVLLENYFFEKLYKIVENLKLKRKPIFWQEVFDNNIPDPNAVIHIWKGNTHEEIYEQVKNITSQNFPVIVSACWYLNYIKYGADWRDEIRGTAPSNSRYYYCDPTNFNGTVAQKELVWGGIAAIWGELVDNTNIEARLWPRASAAAERLWSPAEKTQRAEDAWPRMHELRCRLVSRGYRIQPNNNPDYCPFEFDEPPATKTEL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 47 | N-linked (GlcNAc...) asparagine |
|
||
| 351 | N-linked (GlcNAc...) asparagine |
|
||
| 412 | N-linked (GlcNAc...) asparagine |
|
||
| 457 |
|
|||
| 460 | N-linked (GlcNAc...) asparagine |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CS/DS degradation | Caenorhabditis elegans |
| Glycosphingolipid catabolism | Caenorhabditis elegans |
| Hyaluronan uptake and degradation | Caenorhabditis elegans |
| Keratan sulfate degradation | Caenorhabditis elegans |
| Neutrophil degranulation | Caenorhabditis elegans |
