GlyCosmos Portal

Submissions

C-X-C chemokine receptor type 4

Summary

UniProt ID

Q28474

Gene Symbol

CXCR4

Organism

Macaca fascicularis (crab-eating macaque)

External Links

Re-Glyco: Q28474

Annotation

Keyword

Cell junction
Cell membrane
Disulfide bond
Endosome
G-protein coupled receptor
Isopeptide bond
Lysosome
Phosphoprotein
Proteoglycan
Reference proteome
Sulfation
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
lysosome
plasma membrane
anchoring junction
early endosome
late endosome
external side of plasma membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 8** entries
GO Term
positive regulation of cytosolic calcium ion concentration
calcium-mediated signaling
CXCL12-activated CXCR4 signaling pathway
immune response
neurogenesis
cell chemotaxis
cellular response to cytokine stimulus
brain development

Displaying **all 3** entries
GO Term
C-C chemokine receptor activity
C-C chemokine binding
C-X-C motif chemokine 12 receptor activity

Annotation information from UniProt.

Sequence

MEGISIYTSDNYTEEMGSGDYDSIKEPCFREENAHFNRIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQKPRKLLAEKVVYVGVWIPALLLTIPDFIFASVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites