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Clusterin

Summary

UniProt ID

Q29482

Gene Symbol

CLU

Organism

Equus caballus (horse)

External Links

PubChem: Q29482

Annotation

Keyword

Chaperone
Cytoplasm
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Membrane
Microsome
Mitochondrion
Nucleus
Phosphoprotein
Reference proteome
Secreted
Signal
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
positive regulation of receptor-mediated endocytosis
positive regulation of NF-kappaB transcription factor activity
immune complex clearance
response to misfolded protein
intrinsic apoptotic signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of ubiquitin-dependent protein catabolic process
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of intrinsic apoptotic signaling pathway
negative regulation of amyloid fibril formation

Displaying entries **1 - 10** of 11 in total

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GO Term
mitochondrion
mitochondrial inner membrane
cytosol
spherical high-density lipoprotein particle
chromaffin granule
perinuclear region of cytoplasm
perinuclear endoplasmic reticulum lumen
extracellular space
nucleus
cytoplasm

Displaying **all 3** entries
GO Term
misfolded protein binding
ubiquitin protein ligase binding
unfolded protein binding

Annotation information from UniProt.

Sequence

MKTLLLLVGLLLTLENGQVLGDKAVSDRELQEMSTQGSNYINKEIKNALKGVKQIKNLIEQTNEERKSLLGTLEEAKKKKEGALNDTKDSEMKLKESQGVCNETMTALWEECKPCLKQTCMKFYARVCRSGSGLVGHQLEEFLNQSSPFYFWINGDRIDSLLENDRQQTHVLDVMQDSFDRASSIMDELFQDRFFTREPQDTYYYSPFSSPHRRSSLLFNPKSRFARNIMHFPMYRHLNFNDMFQPFFDMIHQAQQAMNLHLHRLPDQLPMTEFSEGDNHDRTVCKEIRHNSTGCLKMKDQCEKCQEILSVDCSTNNPSQMQLRQELNNSLQLAEKFTKLYDELLQSYQEKMLNTSSLLKQLNEQFSWVSQLANLTQGEDQYYLQVTTVSSHNSDSEVPSGLTRVVVKLFDSYPITVTVPEVVSRNNPKFMETVAEKALQEYRQKNREE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
85	N-linked (GlcNAc...) asparagine	UniProt
102	N-linked (GlcNAc...) asparagine	UniProt
144	N-linked (GlcNAc...) asparagine	UniProt
291	N-linked (GlcNAc...) asparagine	UniProt
328	N-linked (GlcNAc...) asparagine	UniProt
354	N-linked (GlcNAc...) asparagine	UniProt
374	N-linked (GlcNAc...) asparagine	UniProt