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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Lysosomal acid glucosylceramidase
Summary
- UniProt ID
- Q2KHZ8
- Gene Symbol
-
- GBA1
- GBA
- Organism
- Bos taurus (cattle)
Annotation
- Keyword
-
- Cholesterol metabolism
- Disulfide bond
- Glycoprotein
- Glycosidase
- Glycosyltransferase
- Lysosome
- Membrane
- Reference proteome
- Signal
- Sphingolipid metabolism
- Gene Ontology (GO)
| GO Term |
|---|
| lipid glycosylation |
| regulation of TOR signaling |
| cholesterol metabolic process |
| glucosylceramide catabolic process |
| autophagy |
| lysosome organization |
| GO Term |
|---|
| endoplasmic reticulum |
| trans-Golgi network |
| lysosome |
| lysosomal membrane |
| Golgi apparatus |
| GO Term |
|---|
| steryl-beta-glucosidase activity |
| galactosylceramidase activity |
| glucosylceramidase activity |
| glucosyltransferase activity |
Sequence
MELSSPSREEYPMPRGRVGIMAASLMGLLLLHTVSWVSGARPCSPKSFGYSSVVCVCNGTYCDSLDPLTLPDPGTFSRFESTRSGRRMELSLGTIQANRTGTGLLLTLQPDQKFQKVKGFGGAMTDAAALNILALSPAARNLLLKSYFSEEGIEYNIIRVPMASCDFSIRTYTYDDSPDDFQLLNFSLPEEDVKLKIPLIHQALELANRSVSLFASPWTSPTWLKTNGAVNGKGTLKGQAGDLYHKTWARYFVKFLDAYAEHKLRFWAVTAENEPTAGLLTGYPFQCLGFTPEHQRDFIARDLGPILANSTHRDVRLLMLDDQRLLLPRWAQVVLADPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMRYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDIAKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASKKSDLDTVALLRPDGSAVAVVLNRSSKDVPLTIKDPAVGFMETVSPGYSIHTYLWRRQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 58 | N-linked (GlcNAc...) asparagine |
|
||
| 98 | N-linked (GlcNAc...) asparagine |
|
||
| 185 | N-linked (GlcNAc...) asparagine |
|
||
| 208 | N-linked (GlcNAc...) asparagine |
|
||
| 309 | N-linked (GlcNAc...) asparagine |
|
||
| 501 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
