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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hepatocyte growth factor receptor
Summary
- UniProt ID
- Q2QLE0
- Gene Symbol
-
- MET
- Organism
- Sus scrofa (pig)
External Links
- PubChem
- Q2QLE0
Annotation
- Keyword
-
- ATP-binding
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Proto-oncogene
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| basal plasma membrane |
| plasma membrane |
| receptor complex |
| GO Term |
|---|
| hepatocyte growth factor receptor activity |
| ATP binding |
| semaphorin receptor activity |
| protein phosphatase binding |
| identical protein binding |
Sequence
MKAPAVLAPGILVLLFTLVQKSKGECKEALVKSTMNLNMQYQLPNFTAETPIQNVVLHKHHIYLGALNYIYVLNDIDLRKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGIWRDNINMALLVDTYYDDQLISCGSVHRGTCQRHVLPPDNIADIKSEVHCMYSPQVDEEPSQCPDCVVSALGTKVLLSEKDRFINFFVGNTINSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTREEVFNILQAAYVSKPGTQLAKQIGANLNDDILYGVFAQSKPDSAEPMNRSAVCAFPVKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTEFTTALQRIDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRPGLSTPHVNFHLDSHPVSPEVIVEPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCQDKCVQLEECPSGTWTQEICLPTVYKVFPTSAPLEGGTTLTICGWDFGFRRNNKFDLRKTKVLLGNESCTLTLSESTTNTLKCTVGPAMNEHFNMSIVISNGRGTTQYRTFSYVDPVITNISPSFGPKTGGTLLTLTGMHLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTTPTEFPIKLKIDLANREINSFTYREDPIVYEIHPTKSFISGGSTITGVGRNLNSVSVLRMVINVHEAERNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSSEPVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVDGEGDT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 45 | N-linked (GlcNAc...) asparagine |
|
||
| 106 | N-linked (GlcNAc...) asparagine |
|
||
| 203 | N-linked (GlcNAc...) asparagine |
|
||
| 359 | N-linked (GlcNAc...) asparagine |
|
||
| 400 | N-linked (GlcNAc...) asparagine |
|
||
| 406 | N-linked (GlcNAc...) asparagine |
|
||
| 582 | O-linked (Man) threonine |
|
||
| 607 | N-linked (GlcNAc...) asparagine |
|
||
| 635 | N-linked (GlcNAc...) asparagine |
|
||
| 676 | O-linked (Man) threonine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Drug-mediated inhibition of MET activation | Sus scrofa |
| MET Receptor Activation | Sus scrofa |
| MET activates PI3K/AKT signaling | Sus scrofa |
| MET activates PTK2 signaling | Sus scrofa |
| MET activates PTPN11 | Sus scrofa |
| MET activates RAP1 and RAC1 | Sus scrofa |
| MET activates RAS signaling | Sus scrofa |
| MET activates STAT3 | Sus scrofa |
| MET interacts with TNS proteins | Sus scrofa |
| MET receptor recycling | Sus scrofa |
