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Electroneutral sodium bicarbonate exchanger 1

Summary

UniProt ID

Q2Y0W8

Gene Symbol

KIAA0739
NBC
NBC3
NDCBE1
SLC4A8

Gene ID

9498

Organism

Homo sapiens (human)

External Links

GlyGen: Q2Y0W8
The Human Metabolome Database: HMDBP05646
The O-GlcNAc Database: Q2Y0W8
Re-Glyco: Q2Y0W8

Annotation

Keyword

3D-structure
Alternative splicing
Anion exchange
Antiport
Cell membrane
Coiled coil
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Reference proteome
Sodium transport
Synapse
Transmembrane helix
Zinc

Gene Ontology (GO)

Displaying entries **1 - 10** of 18 in total

1

2

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GO Term
glutamatergic synapse
plasma membrane
membrane
dendrite
neuron projection
presynapse
basolateral plasma membrane
apical plasma membrane
synaptic vesicle
synaptic vesicle membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 10** entries
GO Term
bicarbonate transport
regulation of membrane potential
modulation of chemical synaptic transmission
transmembrane transport
basolateral protein secretion
positive regulation of synaptic vesicle exocytosis
sodium ion transmembrane transport
regulation of intracellular pH
chloride transmembrane transport
transport across blood-brain barrier

Displaying **all 8** entries
GO Term
bicarbonate transmembrane transporter activity
zinc ion binding
sodium ion transmembrane transporter activity
identical protein binding
sodium:bicarbonate symporter activity
sodium,bicarbonate:chloride antiporter activity
solute:inorganic anion antiporter activity
chloride transmembrane transporter activity

Annotation information from UniProt.

Sequence

MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALSMNSGNAKEKSLFN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites