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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neutrophil elastase
Summary
- UniProt ID
- Q3UP87
- Gene Symbol
-
- Elane
- Ela2
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0004873
- PubChem
- Q3UP87
- The Human Metabolome Database
- HMDBP13386
Annotation
- Keyword
-
- Disulfide bond
- Glycoprotein
- Reference proteome
- Serine protease
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cell surface |
| extracellular space |
| cytoplasm |
| secretory granule |
| collagen-containing extracellular matrix |
| transcription repressor complex |
| GO Term |
|---|
| serine-type endopeptidase activity |
| transcription corepressor activity |
| protease binding |
| heparin binding |
| peptidase activity |
| cytokine binding |
Sequence
MALGRLSSRTLAAMLLALFLGGPALASEIVGGRPARPHAWPFMASLQRRGGHFCGATLIARNFVMSAAHCVNGLNFRSVQVVLGAHDLRRQERTRQTFSVQRIFENGFDPSQLLNDIVIIQLNGSATINANVQVAQLPAQGQGVGDRTPCLAMGWGRLGTNRPSPSVLQELNVTVVTNMCRRRVNVCTLVPRRQAGICFGDSGGPLVCNNLVQGIDSFIRGGCGSGLYPDAFAPVAEFADWINSIIRSHNDHLLTHPKDREGRTN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 123 | N-linked (GlcNAc...) asparagine |
|
||
| 172 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Mus musculus |
| Antimicrobial peptides | Mus musculus |
| Degradation of the extracellular matrix | Mus musculus |
| Neutrophil degranulation | Mus musculus |
| Pyroptosis | Mus musculus |
| Regulation of Complement cascade | Mus musculus |
