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MIRAGE
Guanylyl cyclase C
Summary
- UniProt ID
- Q3UWA6
- Gene Symbol
-
- Guc2c
- Gucy2c
- Gene ID
- 14917
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Endoplasmic reticulum
- GTP-binding
- Glycoprotein
- Lyase
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- cGMP biosynthesis
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum membrane |
| plasma membrane |
| GO Term |
|---|
| intracellular signal transduction |
| regulation of cell population proliferation |
| response to toxic substance |
| GO Term |
|---|
| GTP binding |
| guanylate cyclase activity |
| protein kinase activity |
| ATP binding |
| toxic substance binding |
Sequence
MTSLLGLAVRLLLFQPALMVFWASQVRQNCRNGSYEISVLMMDNSAYKEPMQNLREAVEEGLDIVRKRLREADLNVTVNATFIYSDGLIHKSGDCRSSTCEGLDLLREITRDHKMGCALMGPSCTYSTFQMYLDTELNYPMISAGSYGLSCDYKETLTRILPPARKLMYFLVDFWKVNNASFKPFSWNSSYVYKNGSEPEDCFWYLNALEAGVSYFSEVLNFKDVLRRSEQFQEILTGHNRKSNVIVMCGTPESFYDVKGDLQVAEDTVVILVDLFSNHYFEENTTAPEYMDNVLVLTLPSEQSTSNTSVAERFSSGRSDFSLAYLEGTLLFGHMLQTFLENGENVTGPKFARAFRNLTFQGFAGPVTLDDSGDIDNIMSLLYVSLDTRKYKVLMKYDTHKNKTIPVAENPNFIWKNHKLPNDVPGLGPQILMIAVFTLTGILVVLLLIALLVLRKYRRDHALRQKKWSHIPSENIFPLETNETNHISLKIDDDRRRDTIQRVRQCKYDKKKVILKDLKHSDGNFSEKQKIDLNKLLQSDYYNLTKFYGTVKLDTRIFGVVEYCERGSLREVLNDTISYPDGTFMDWEFKISVLNDIAKGMSYLHSSKIEVHGRLKSTNCVVDSRMVVKITDFGCNSILPPKKDLWTAPEHLRQATISQKGDVYSFAIIAQEIILRKETFYTLSCRDHNEKIFRVENSYGKPFRPDLFLETADEKELEVYLLVKSCWEEDPEKRPDFKKIESTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADHLNFMLLPRLVVKSLKEKGIVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDQIVDHHDVYKVETIGDAYVVASGLPMRNGNRHAVDISKMALDILSFIGTFELEHLPGLPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHMSSSTITILKRTDCQFLYEVRGETYLKGRGTETTYWLTGMKDQEYNLPSPPTVENQQRLQTEFSDMIVSALQKRQASGKKSRRPTRVASYKKGFLEYMQLNNSDHDSTYF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 32 | N-linked (GlcNAc...) asparagine |
|
||
| 75 | N-linked (GlcNAc...) asparagine |
|
||
| 79 | N-linked (GlcNAc...) asparagine |
|
||
| 179 | N-linked (GlcNAc...) asparagine |
|
||
| 188 | N-linked (GlcNAc...) asparagine |
|
||
| 195 | N-linked (GlcNAc...) asparagine |
|
||
| 284 | N-linked (GlcNAc...) asparagine |
|
||
| 307 | N-linked (GlcNAc...) asparagine |
|
||
| 345 | N-linked (GlcNAc...) asparagine |
|
||
| 402 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Digestion | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060611 | abdominal obesity-metabolic syndrome | |
| DOID:9970 | obesity |
