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Protein mono-ADP-ribosyltransferase PARP10

Summary

UniProt ID

Q53GL7

Gene Symbol

PARP10

Organism

Homo sapiens (human)

External Links

GlyGen: Q53GL7
PubChem: Q53GL7
The Human Metabolome Database: HMDBP08867
The O-GlcNAc Database: Q53GL7
O-GlcNAcAtlas: Q53GL7

Annotation

Keyword

3D-structure
ADP-ribosylation
Acetylation
Cytoplasm
DNA repair
Glycosyltransferase
NAD
Nucleotidyltransferase
Nucleus
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
negative regulation of NF-kappaB transcription factor activity
negative regulation of fibroblast proliferation
chromatin organization
viral protein processing
negative regulation of gene expression
translesion synthesis
protein poly-ADP-ribosylation
protein auto-ADP-ribosylation
negative regulation of protein K63-linked ubiquitination
NAD biosynthesis via nicotinamide riboside salvage pathway

Displaying **all 5** entries
GO Term
Golgi apparatus
cytosol
nucleus
nucleolus
cytoplasm

Displaying **all 7** entries
GO Term
transcription corepressor activity
NAD+ ADP-ribosyltransferase activity
nucleotidyltransferase activity
NAD+- protein-lysine ADP-ribosyltransferase activity
DNA-binding transcription factor binding
K63-linked polyubiquitin modification-dependent protein binding
NAD+-protein ADP-ribosyltransferase activity

Annotation information from UniProt.

Sequence

MVAMAEAEAGVAVEVRGLPPAVPDELLTLYFENRRRSGGGPVLSWQRLGCGGVLTFREPADAERVLAQADHELHGAQLSLRPAPPRAPARLLLQGLPPGTTPQRLEQHVQALLRASGLPVQPCCALASPRPDRALVQLPKPLSEADVRVLEEQAQNLGLEGTLVSLARVPQARAVRVVGDGASVDLLLLELYLENERRSGGGPLEDLQRLPGPLGTVASFQQWQVAERVLQQEHRLQGSELSLVPHYDILEPEELAENTSGGDHPSTQGPRATKHALLRTGGLVTALQGAGTVTMGSGEEPGQSGASLRTGPMVQGRGIMTTGSGQEPGQSGTSLRTGPMGSLGQAEQVSSMPMGSLEHEGLVSLRPVGLQEQEGPMSLGPVGSAGPVETSKGLLGQEGLVEIAMDSPEQEGLVGPMEITMGSLEKAGPVSPGCVKLAGQEGLVEMVLLMEPGAMRFLQLYHEDLLAGLGDVALLPLEGPDMTGFRLCGAQASCQAAEEFLRSLLGSISCHVLCLEHPGSARFLLGPEGQHLLQGLEAQFQCVFGTERLATATLDTGLEEVDPTEALPVLPGNAHTLWTPDSTGGDQEDVSLEEVRELLATLEGLDLDGEDWLPRELEEEGPQEQPEEEVTPGHEEEEPVAPSTVAPRWLEEEAALQLALHRSLEPQGQVAEQEEAAALRQALTLSLLEQPPLEAEEPPDGGTDGKAQLVVHSAFEQDVEELDRALRAALEVHVQEETVGPWRRTLPAELRARLERCHGVSVALRGDCTILRGFGAHPARAARHLVALLAGPWDQSLAFPLAASGPTLAGQTLKGPWNNLERLAENTGEFQEVVRAFYDTLDAARSSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNRSFCGRNATVYGKGVYFARRASLSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPLRGPGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLITCEHVPRASPDDPSGLPGRSPDT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites