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MIRAGE
Cathepsin K
Summary
- UniProt ID
- Q5E968
- Gene Symbol
-
- CTSK
- Gene ID
- 513038
- Organism
- Bos taurus (domestic cattle)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Glycoprotein
- Lysosome
- Reference proteome
- Secreted
- Signal
- Thiol protease
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| lysosome |
| apical plasma membrane |
| GO Term |
|---|
| thyroid hormone generation |
| immune response |
| proteolysis involved in protein catabolic process |
| positive regulation of apoptotic signaling pathway |
| GO Term |
|---|
| cysteine-type endopeptidase activity |
| cysteine-type endopeptidase activator activity involved in apoptotic process |
Sequence
MWGLTVLLLPVVSFALYPEEILDTQWELWKKTYRKQYNSKGDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPASRSRSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQDENCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPISVAIDASLTSFQFYRKGVYYDENCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 103 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Bos taurus |
| Collagen degradation | Bos taurus |
| Degradation of the extracellular matrix | Bos taurus |
| MHC class II antigen presentation | Bos taurus |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | Bos taurus |
| Trafficking and processing of endosomal TLR | Bos taurus |
