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Toll-like receptor 9

Summary

UniProt ID

Q5I2M4

Gene Symbol

TLR9

Gene ID

494547

Organism

Ovis aries (sheep)

External Links

PubChem: Q5I2M4
Re-Glyco: Q5I2M4

Annotation

Keyword

Cytoplasmic vesicle
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
Lysosome
Palmitate
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
early phagosome
lysosome
plasma membrane
endosome
endoplasmic reticulum
endoplasmic reticulum membrane
endolysosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 16 in total

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GO Term
positive regulation of immunoglobulin production
inflammatory response
positive regulation of B cell proliferation
positive regulation of type II interferon production
innate immune response
regulation of B cell differentiation
positive regulation of B cell activation
defense response to virus
regulation of primary metabolic process
positive regulation of toll-like receptor 9 signaling pathway

Displaying **all 4** entries
GO Term
pattern recognition receptor activity
protein homodimerization activity
siRNA binding
unmethylated CpG binding

Annotation information from UniProt.

Sequence

MGPYCAPHPLSLLVQAAALAAALAQGTLPAFLPCELQPRGKVNCNWLFLKSVPRFSAGAPRANVTSLSLISNRIHHLHDSDFVHLSNLRVLNLKWNCPPAGLSPMHFPCRMTIEPNTFLAVPTLEELNLSYNGITTVPALPSSLVSLSLSRTSILVLGPTHFTGLHALRFLYMDGNCYYKNPCQQAVEVAPGALLGLGNLTHLSLKYNNLTEVPRRLPPSLDTLLLSYNHIITLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKNFPKLHPDTFSHLSRLEGLVLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTIFRNLTQLRRLNLSFNYHKKVSFAHLQLAPSFGGLVSLEKLDMHGIFFRSLTNTTLRPLTQLPKLQSLSLQLNFINQAELSIFGAFPSLLFVDLSDNRISGAARPVAALGEVDSGVEVWRWPRGLAPGPLAAVSAKDFMPSCNLNFTLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNGSQFVPLTRLRVLDLSYNKLDLYHGRSFTELPQLEALDLSYNSQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSKNHLHTLLPRHLDNLPKSLRQLRLRDNNLAFFNWSSLTVLPQLEALDLAGNQLKALSNGSLPPGTRLQKLDVSSNSIGFVTPGFFVLANRLKELNLSANALKTVDPFWFGRLTETLKILDVSANPLHCACGAAFVDFLLEMQAAVPGLSRRVTCGSPGQLQGRSIFAQDLRLCLDETLSLDCFGFSLLMVALGLAVPMLHHLCGWDLWYCFHLCLAHLPRRRRQRGEDTLLYDAFVVFDKAQSAVADWVYNELRVQLEERRGRRALRLCLEERDWLPGKTLFENLWASVYSSRKTMFVLDHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILRPAAYRSRYVRLRQRLCRQSVLLWPHQPSGQGSFWANLGMALTRDNRHFYNRNFCRGPTTAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	Description	Source
63	N-linked (GlcNAc...) asparagine	UniProt
128	N-linked (GlcNAc...) asparagine	UniProt
199	N-linked (GlcNAc...) asparagine	UniProt
209	N-linked (GlcNAc...) asparagine	UniProt
241	N-linked (GlcNAc...) asparagine	UniProt
331	N-linked (GlcNAc...) asparagine	UniProt
339	N-linked (GlcNAc...) asparagine	UniProt
380	N-linked (GlcNAc...) asparagine	UniProt
472	N-linked (GlcNAc...) asparagine	UniProt
511	N-linked (GlcNAc...) asparagine	UniProt