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Tripeptidyl-peptidase 1

Summary

UniProt ID

Q5IS74

Gene Symbol

TPP1
CLN2

Organism

Pan troglodytes (chimpanzee)

External Links

PubChem: Q5IS74

Annotation

Keyword

Autocatalytic cleavage
Calcium
Disulfide bond
Glycoprotein
Lysosome
Metal-binding
Reference proteome
Serine protease
Signal
Zymogen

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
proteolysis
nervous system development
central nervous system development
bone resorption
peptide catabolic process

Displaying **all 5** entries
GO Term
membrane raft
recycling endosome
lysosome
Golgi apparatus
melanosome

Displaying **all 8** entries
GO Term
peptidase activity
metal ion binding
endopeptidase activity
serine-type endopeptidase activity
serine-type peptidase activity
tripeptidyl-peptidase activity
lysophosphatidic acid binding
sulfatide binding

Annotation information from UniProt.

Sequence

MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLRTVQKWLLAAGARKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
210	N-linked (GlcNAc...) asparagine	UniProt
222	N-linked (GlcNAc...) asparagine	UniProt
286	N-linked (GlcNAc...) asparagine	UniProt
313	N-linked (GlcNAc...) asparagine	UniProt
443	N-linked (GlcNAc...) asparagine	UniProt