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Eukaryotic initiation factor 4A-II
Summary
- UniProt ID
- Q5RKI1
- Gene Symbol
-
- Eif4a2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Direct protein sequencing
- Helicase
- Initiation factor
- Phosphoprotein
- RNA-binding
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| cellular response to leukemia inhibitory factor |
| cytoplasmic translational initiation |
| GO Term |
|---|
| perinuclear region of cytoplasm |
| GO Term |
|---|
| RNA binding |
| ATP hydrolysis activity |
| RNA helicase activity |
| translation initiation factor activity |
| ATP binding |
Sequence
MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | Rattus norvegicus |
| Deadenylation of mRNA | Rattus norvegicus |
| ISG15 antiviral mechanism | Rattus norvegicus |
| L13a-mediated translational silencing of Ceruloplasmin expression | Rattus norvegicus |
| Ribosomal scanning and start codon recognition | Rattus norvegicus |
| Translation initiation complex formation | Rattus norvegicus |
