GlyCosmos Portal

Submissions

E3 ubiquitin-protein ligase DCST1

Summary

UniProt ID

Q5T197

Gene Symbol

DCST1

Organism

Homo sapiens (human)

External Links

GlyGen: Q5T197

Annotation

Keyword

Alternative splicing
Cell membrane
Cytoplasmic vesicle
Glycoprotein
Innate immunity
Reference proteome
Transferase
Transmembrane helix
Ubl conjugation pathway
Zinc-finger

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
innate immune response
ubiquitin-dependent protein catabolic process
fusion of sperm to egg plasma membrane involved in single fertilization
protein ubiquitination
sperm-egg recognition
negative regulation of type I interferon-mediated signaling pathway

Displaying **all 2** entries
GO Term
plasma membrane
acrosomal membrane

Displaying **all 2** entries
GO Term
ubiquitin protein ligase activity
metal ion binding

Annotation information from UniProt.

Sequence

MDIKHHQNGTRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLLAIGLFQLLVNPMNIYEEQKIMFLYSLVGLGAMGWGTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGPVANLRHNLNNVIASLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSKELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGREARQAPASRLHLSTQKMYELKTKLRCSYVVNQAILSCRRWFDRKHEQCMKHIWVPLLTHLLCLPMKFKFFCGIAKVMEVWCRNRIPVEGNFGQTYDSLNQSIRGLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVRDYVYRQEARLEWALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPLRKAEEKTVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHHSFLQYSFRSSHKLEVKVGGDSMLARLLRKTIGALNTSSETVMESNNMPCLPQPVGLDARAYWRAAVPIGLLVCLCLLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCRRCVVCQAPETPESYVCRTLDCEAVYCWSCWDDMRQRCPVCTPREELSSSAFSDSNDDTAYAG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	GlyTouCan ID	Source
156	N-linked (GlcNAc...) asparagine		UniProt GlyGen
189	N-linked (GlcNAc...) asparagine		UniProt GlyGen
321	N-linked (GlcNAc...) asparagine	G41840AI G39446WN	UniProt GlyGen
349	N-linked (GlcNAc...) asparagine		UniProt GlyGen
525	N-linked (GlcNAc...) asparagine		UniProt GlyGen