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Tau-tubulin kinase 1

Summary

UniProt ID

Q5TCY1

Gene Symbol

TTBK1
BDTK
KIAA1855

Organism

Homo sapiens (human)

External Links

GlyGen: Q5TCY1
PubChem: Q5TCY1
The Human Metabolome Database: HMDBP08089
The O-GlcNAc Database: Q5TCY1

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Coiled coil
Cytoplasm
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

1

2

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GO Term
protein phosphorylation
signal transduction
learning or memory
positive regulation of gene expression
negative regulation of gene expression
peptidyl-tyrosine phosphorylation
substantia nigra development
negative regulation of protein binding
positive regulation of protein polymerization
positive regulation of astrocyte activation

Displaying **all 6** entries
GO Term
nucleus
neuronal cell body
cytosol
nucleoplasm
microtubule associated complex
perinuclear region of cytoplasm

Displaying **all 6** entries
GO Term
protein serine/threonine kinase activity
protein tyrosine kinase activity
tau-protein kinase activity
tau protein binding
ATP binding
protein serine kinase activity

Annotation information from UniProt.

Sequence

MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGAR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites