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Nuclear factor erythroid 2-related factor 2

Summary

UniProt ID

Q60795

Gene Symbol

Nfe2l2
Nrf2

Organism

Mus musculus (house mouse)

External Links

PubChem: Q60795

Annotation

Keyword

3D-structure
Acetylation
Activator
Cytoplasm
DNA-binding
Glycation
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **31 - 40** of 42 in total

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GO Term
positive regulation of neuron projection development
positive regulation of blood coagulation
cellular response to oxidative stress
positive regulation of blood vessel endothelial cell migration
positive regulation of reactive oxygen species metabolic process
negative regulation of hematopoietic stem cell differentiation
negative regulation of vascular associated smooth muscle cell migration
negative regulation of endothelial cell apoptotic process
cellular response to hypoxia
proteasome-mediated ubiquitin-dependent protein catabolic process

Displaying entries **1 - 10** of 11 in total

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GO Term
cytosol
nucleoplasm
transcription regulator complex
centrosome
protein-DNA complex
RNA polymerase II transcription regulator complex
chromatin
nucleus
cytoplasm
Golgi apparatus

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GO Term
DNA binding
transcription factor binding
RNA polymerase II-specific DNA-binding transcription factor binding
protein domain specific binding
ubiquitin protein ligase binding
transcription cis-regulatory region binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQKDYELEKQKKLEKERQEQLQKEQEKAFFAQFQLDEETGEFLPIQPAQHIQTDTSGSASYSQVAHIPKQDALYFEDCMQLLAETFPFVDDHESLALDIPSHAESSVFTAPHQAQSLNSSLEAAMTDLSSIEQDMEQVWQELFSIPELQCLNTENKQLADTTAVPSPEATLTEMDSNYHFYSSISSLEKEVGNCGPHFLHGFEDSFSSILSTDDASQLTSLDSNPTLNTDFGDEFYSAFIAEPSDGGSMPSSAAISQSLSELLDGTIEGCDLSLCKAFNPKHAEGTMEFNDSDSGISLNTSPSRASPEHSVESSIYGDPPPGFSDSEMEELDSAPGSVKQNGPKAQPAHSPGDTVQPLSPAQGHSAPMRESQCENTTKKEVPVSPGHQKAPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRRLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
454	N-linked (Glc) (glycation) lysine	UniProt
464	N-linked (Glc) (glycation) lysine	UniProt
479	N-linked (Glc) (glycation) lysine	UniProt
491	N-linked (Glc) (glycation) arginine	UniProt
561	N-linked (Glc) (glycation) arginine	UniProt
566	N-linked (Glc) (glycation) lysine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	Mus musculus
KEAP1-NFE2L2 pathway	Mus musculus
Neddylation	Mus musculus
Nuclear events mediated by NFE2L2	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements