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Voltage-dependent anion-selective channel protein 1

Summary

UniProt ID

Q60932

Gene Symbol

Vdac1
Vdac5

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60932
PubChem: Q60932
The O-GlcNAc Database: Q60932
RaftProt: Q60932
O-GlcNAcAtlas: Q60932

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Apoptosis
Cell membrane
Direct protein sequencing
Isopeptide bond
Lipid transport
Lipid-binding
Mitochondrion outer membrane
NAD
Phosphoprotein
Porin
Reference proteome
Transmembrane beta strand
Ubl conjugation

Gene Ontology (GO)

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GO Term
negative regulation of calcium import into the mitochondrion
regulation of mitophagy
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
apoptotic process
chemical synaptic transmission
epithelial cell differentiation
negative regulation of apoptotic process
negative regulation of reactive oxygen species metabolic process
behavioral fear response
acetyl-CoA biosynthetic process from pyruvate

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GO Term
postsynaptic density membrane
plasma membrane
membrane
protein-containing complex
myelin sheath
presynaptic active zone membrane
mitochondrion
mitochondrial inner membrane
mitochondrial nucleoid
membrane raft

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GO Term
ceramide binding
monoatomic anion channel activity
voltage-gated monoatomic anion channel activity
protein-containing complex binding
protein kinase binding
cholesterol binding
phosphatidylcholine binding
identical protein binding
transmembrane transporter binding
nucleotide binding

Annotation information from UniProt.

Sequence

MCSFFLVLLLWQNMAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites