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Lymphocyte activation gene 3 protein

Summary

UniProt ID

Q61790

Gene Symbol

Lag3

Organism

Mus musculus (house mouse)

External Links

PubChem: Q61790

Annotation

Keyword

3D-structure
Adaptive immunity
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
cell surface receptor signaling pathway
T cell activation
natural killer cell mediated cytotoxicity
regulation of immune response
negative regulation of interleukin-2 production
negative regulation of regulatory T cell differentiation
positive regulation of natural killer cell mediated cytotoxicity
negative regulation of T cell activation
adaptive immune response
plasmacytoid dendritic cell activation

Displaying **all 2** entries
GO Term
extracellular region
external side of plasma membrane

Displaying **all 2** entries
GO Term
MHC class II protein binding
transmembrane signaling receptor activity

Annotation information from UniProt.

Sequence

MREDLLLGFLLLGLLWEAPVVSSGPGKELPVVWAQEGAPVHLPCSLKSPNLDPNFLRRGGVIWQHQPDSGQPTPIPALDLHQGMPSPRQPAPGRYTVLSVAPGGLRSGRQPLHPHVQLEERGLQRGDFSLWLRPALRTDAGEYHATVRLPNRALSCSLRLRVGQASMIASPSGVLKLSDWVLLNCSFSRPDRPVSVHWFQGQNRVPVYNSPRHFLAETFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVLGLEPVAPLTVYAAEGSRVELPCHLPPGVGTPSLLIAKWTPPGGGPELPVAGKSGNFTLHLEAVGLAQAGTYTCSIHLQGQQLNATVTLAVITVTPKSFGLPGSRGKLLCEVTPASGKERFVWRPLNNLSRSCPGPVLEIQEARLLAERWQCQLYEGQRLLGATVYAAESSSGAHSARRISGDLKGGHLVLVLILGALSLFLLVAGAFGFHWWRKQLLLRRFSALEHGIQPFPAQRKIEELERELETEMGQEPEPEPEPQLEPEPRQL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
184	N-linked (GlcNAc...) asparagine	UniProt
244	N-linked (GlcNAc...) asparagine	UniProt
309	N-linked (GlcNAc...) asparagine	UniProt
337	N-linked (GlcNAc...) asparagine	UniProt
381	N-linked (GlcNAc...) asparagine	UniProt