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MIRAGE
Mitogen-activated protein kinase kinase kinase 7
Summary
- UniProt ID
- Q62073
- Gene Symbol
-
- Map3k7
- Tak1
- Gene ID
- 26409
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Apoptosis
- Cell membrane
- Cytoplasm
- Isopeptide bond
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Stress response
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cytosol |
| postsynaptic density |
Sequence
MSTASAASSSSSSSASEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIVATAGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPARSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 205 |
|
|||
| 342 |
|
|||
| 374 |
|
|||
| 383 |
|
|||
| 412 |
|
|||
| 444 |
|
|
G31852PQ
G84349RE
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ALPK1 signaling pathway | Mus musculus |
| CLEC7A (Dectin-1) signaling | Mus musculus |
| Ca2+ pathway | Mus musculus |
| Downstream TCR signaling | Mus musculus |
| FCERI mediated NF-kB activation | Mus musculus |
| IRAK2 mediated activation of TAK1 complex | Mus musculus |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Mus musculus |
| Interleukin-1 signaling | Mus musculus |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | Mus musculus |
| NOD1/2 Signaling Pathway | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:384 | Wolff-Parkinson-White syndrome |
