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Protein kinase C iota type
Summary
- UniProt ID
- Q62074
- Gene Symbol
-
- Pkcl
- Prkci
- Gene ID
- 18759
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Cytoplasm
- Developmental protein
- Endosome
- Membrane
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Tumor suppressor
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| Golgi membrane |
| endosome |
| cytosol |
| apical plasma membrane |
| apical part of cell |
| brush border |
| bicellular tight junction |
| microtubule cytoskeleton |
Sequence
MPTQRDSSTMSHTVACGGGGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCSEVRDMCSFDNEQPFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPPEPMMPMDQTMHPDHTQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV
Glycosylation Sites
G01650EU
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| KEAP1-NFE2L2 pathway | Mus musculus |
| Pre-NOTCH Transcription and Translation | Mus musculus |
| Tight junction interactions | Mus musculus |
| p75NTR recruits signalling complexes | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060611 | abdominal obesity-metabolic syndrome | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
