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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Sonic hedgehog protein
Summary
- UniProt ID
- Q62226
- Gene Symbol
-
- Shh
- Hhg1
- Organism
- Mus musculus (house mouse)
External Links
- PubChem
- Q62226
Annotation
- Keyword
-
- 3D-structure
- Autocatalytic cleavage
- Calcium
- Cell membrane
- Developmental protein
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Metal-binding
- Palmitate
- Protease
- Reference proteome
- Signal
- Transferase
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| hair follicle development |
| vasculature development |
| positive regulation of neuroblast proliferation |
| positive regulation of mesenchymal cell proliferation |
| osteoblast development |
| lymphoid progenitor cell differentiation |
| GO Term |
|---|
| membrane raft |
| nucleoplasm |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| endoplasmic reticulum lumen |
| synaptic vesicle |
| cell surface |
| GO Term |
|---|
| calcium ion binding |
| glycosaminoglycan binding |
| peptidase activity |
| laminin-1 binding |
| patched binding |
| zinc ion binding |
| cholesterol-protein transferase activity |
Sequence
MLLLLARCFLVILASSLLVCPGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLRPGDRVLAADDQGRLLYSDFLTFLDRDEGAKKVFYVIETLEPRERLLLTAAHLLFVAPHNDSGPTPGPSALFASRVRPGQRVYVVAERGGDRRLLPAAVHSVTLREEEAGAYAPLTAHGTILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDGGGGGSIPAAQSATEARGAEPTAGIHWYSQLLYHIGTWLLDSETMHPLGMAVKSS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 279 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of SMO | Mus musculus |
| Hedgehog ligand biogenesis | Mus musculus |
| Ligand-receptor interactions | Mus musculus |
| Release of Hh-Np from the secreting cell | Mus musculus |
