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Vesicular acetylcholine transporter

Summary

UniProt ID

Q62666

Gene Symbol

Slc18a3
Vacht
Vat

Gene ID

60422

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q62666
Re-Glyco: Q62666

Annotation

Keyword

Cytoplasmic vesicle
Glycoprotein
Neurotransmitter transport
Reference proteome
Synapse
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

1

2

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GO Term
axon
neuromuscular junction
neuron projection
synaptic vesicle
AP-1 adaptor complex
AP-2 adaptor complex
synaptic vesicle membrane
terminal bouton
axon terminus
cytoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 8** entries
GO Term
chemical synaptic transmission
neurotransmitter loading into synaptic vesicle
positive regulation of long-term synaptic potentiation
positive regulation of acetylcholine secretion, neurotransmission
acetylcholine transport
serotonin uptake
acetylcholine uptake
positive regulation of neuromuscular junction development

Displaying **all 3** entries
GO Term
acetylcholine transmembrane transporter activity
monoamine:proton antiporter activity
acetylcholine:proton antiporter activity

Annotation information from UniProt.

Sequence

MEPTAPTGQARAAATKLSEAVGAALQEPQRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGSEGPTLVSEVWEPTLPPPTLANASAYLANTSASPTAAGSARSILRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMVWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGVSSCVVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLREVQGKDGGEPCSPPGPFDGCEDDYNYYSRS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
89	N-linked (GlcNAc...) asparagine			UniProt
96	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Acetylcholine Neurotransmitter Release Cycle	Rattus norvegicus
Cargo recognition for clathrin-mediated endocytosis	Rattus norvegicus
Clathrin-mediated endocytosis	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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International Collaboration

Acknowledgements