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ATP-binding cassette sub-family C member 2

Summary

UniProt ID

Q63120

Gene Symbol

Abcc2
Cmoat
Cmrp
Mrp2

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q63120

Annotation

Keyword

3D-structure
ATP-binding
Cell membrane
Glycoprotein
Lipid transport
Phosphoprotein
Reference proteome
Repeat
Translocase
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 39 in total

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GO Term
response to oxidative stress
female pregnancy
negative regulation of gene expression
organic anion transport
transmembrane transport
response to organic cyclic compound
bile acid and bile salt transport
bilirubin transport
response to estradiol
response to glucagon

Displaying **all 7** entries
GO Term
plasma membrane
membrane
apical plasma membrane
brush border membrane
intercellular canaliculus
intracellular canaliculus
cell surface

Displaying **all 9** entries
GO Term
ATP hydrolysis activity
ATPase-coupled transmembrane transporter activity
xenobiotic transmembrane transporter activity
ATP binding
ABC-type xenobiotic transporter activity
organic anion transmembrane transporter activity
bilirubin transmembrane transporter activity
ABC-type glutathione S-conjugate transporter activity
protein domain specific binding

Annotation information from UniProt.

Sequence

MDKFCNSTFWDLSLLESPEADLPLCFEQTVLVWIPLGFLWLLAPWQLYSVYRSRTKRSSITKFYLAKQVFVVFLLILAAIDLSLALTEDTGQATVPPVRYTNPILYLCTWLLVLAVQHSRQWCVRKNSWFLSLFWILSVLCGVFQFQTLIRALLKDSKSNMAYSYLFFVSYGFQIVLLILTAFSGPSDSTQTPSVTASFLSSITFSWYDRTVLKGYKHPLTLEDVWDIDEGFKTRSVTSKFEAAMTKDLQKARQAFQRRLQKSQRKPEATLHGLNKKQSQSQDVLVLEEAKKKSEKTTKDYPKSWLIKSLFKTFHVVILKSFILKLIHDLLVFLNPQLLKLLIGFVKSSNSYVWFGYICAILMFAVTLIQSFCLQSYFQHCFVLGMCVRTTVMSSIYKKALTLSNLARKQYTIGETVNLMSVDSQKLMDATNYMQLVWSSVIQITLSIFFLWRELGPSILAGVGVMVLLIPVNGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRKKELKNLLRFGQLQSLLIFILQITPILVSVVTFSVYVLVDSANVLNAEKAFTSITLFNILRFPLSMLPMVTSSILQASVSVDRLERYLGGDDLDTSAIRRVSNFDKAVKFSEASFTWDPDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLVSAMLGEMENVHGHITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVGKHIFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKGVFARNWKTFMKHSGPEGEATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMRRENSLRRTLSRSSRSSSRRGKSLKNSLKIKNVNVLKEKEKEVEGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSILFIILFYGLNNVAFIGSNLWLSAWTSDSDNLNGTNNSSSHRDMRIGVFGALGLAQGICLLISTLWSIYACRNASKALHGQLLTNILRAPMRFFDTTPTGRIVNRFSGDISTVDDLLPQTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVATSRQLRRLDSVTKSPIYSHFSETVTGLPIIRAFEHQQRFLAWNEKQIDINQKCVFSWITSNRWLAIRLELVGNLVVFCSALLLVIYRKTLTGDVVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERISEYINVENEAPWVTDKRPPADWPRHGEIQFNNYQVRYRPELDLVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDVASIGLHDLRERLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWRALELAHLRSFVSGLQLGLLSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSNRGSFYLMAKEAGIENVNHTEL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
6	N-linked (GlcNAc...) asparagine	UniProt
1007	N-linked (GlcNAc...) asparagine	UniProt
1010	N-linked (GlcNAc...) asparagine	UniProt
1011	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
ABC-family proteins mediated transport	Rattus norvegicus
APAP ADME	Rattus norvegicus
Aspirin ADME	Rattus norvegicus
Atorvastatin ADME	Rattus norvegicus
Heme degradation	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements