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MIRAGE
Advanced glycosylation end product-specific receptor
Summary
- UniProt ID
- Q63495
- Gene Symbol
-
- Ager
- Rage
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Inflammatory response
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| axon |
| neuronal cell body |
| basal plasma membrane |
| cell surface |
| apical plasma membrane |
Sequence
MPTGTVARAWVLVLALWGAVAGGQNITARIGEPLMLSCKGAPKKPTQKLEWKLNTGRTEAWKVLSPQGDPWDSVARILPNGSLLLPAIGIVDEGTFRCRATNRLGKEVKSNYRVRVYQIPGKPEIVNPASELTANVPNKVGTCVSEGSYPAGTLSWHLDGKPLIPDGKGTVVKEETRRHPETGLFTLRSELTVTPAQGGTTPTYSCSFSLGLPRRRPLNTAPIQPRVREPLPPEGIQLLVEPEGGTVAPGGTVTLTCAISAQPPPQIHWIKDGTPLPLAPSPVLLLPEVGHEDEGIYSCVATHPSHGPQESPPVNIRVTETGDEGQAAGSVDGSGLGTLALALGILGGLGIAALLIGAILWRKRQPRLEERKAPESQEDEEERAELNQSEEAEMPENGAGGP
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Advanced glycosylation endproduct receptor signaling | Rattus norvegicus |
| TAK1-dependent IKK and NF-kappa-B activation | Rattus norvegicus |
| TRAF6 mediated NF-kB activation | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050855 | renal fibrosis | |
| DOID:10652 | Alzheimer's disease | |
| DOID:12918 | thromboangiitis obliterans | |
| DOID:1875 | impotence | |
| DOID:2841 | asthma | |
| DOID:77 | gastrointestinal system disease | |
| DOID:8947 | diabetic retinopathy | |
| DOID:9352 | type 2 diabetes mellitus |
