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Monocyte differentiation antigen CD14

Summary

UniProt ID

Q63691

Gene Symbol

Cd14

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q63691

Annotation

Keyword

Cell membrane
Disulfide bond
GPI-anchor
Golgi apparatus
Inflammatory response
Innate immunity
Leucine-rich repeat
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 24 in total

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GO Term
positive regulation of cytokine production
inflammatory response
response to bacterium
positive regulation of type II interferon production
innate immune response
positive regulation of endocytosis
cell surface pattern recognition receptor signaling pathway
receptor-mediated endocytosis
response to magnesium ion
positive regulation of type I interferon production

Displaying **all 6** entries
GO Term
Golgi apparatus
external side of plasma membrane
cell surface
extracellular space
membrane raft
lipopolysaccharide receptor complex

Displaying **all 3** entries
GO Term
lipopolysaccharide binding
lipopolysaccharide immune receptor activity
lipoteichoic acid binding

Annotation information from UniProt.

Sequence

MKLMLGLLLLPLTLVHASPATPEPCELDQDEESVRCYCNFSDPQPNWSSAFLCAGAEDVEFYGGGRSLEYLLKRVDTEANLGQYTDIIRSLPLKRLTVRSARVPTQILFGTLRVLGYSGLRELTLENLEVTGTALSPLLDATGPDLNTLSLRNVSWATTDTWLAELQQWLKPGLKVLSIAQAHSLNFSCKQVGVFPALATLDLSDNPELGEKGLISALCPHKFPTLQVLALRNAGMETTSGVCSALAAARVPLQALDLSHNSLRDTAGTPSCDWPSQLNSLNLSFTGLEHVPKGLPAKLSVLDLSYNRLDRKPRPEELPEVGSLSLTGNPFLHSESQSEAYNSGVVIATALSPGSAGLSGTLALLLGHRLFV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
39	N-linked (GlcNAc...) asparagine	UniProt
46	N-linked (GlcNAc...) asparagine	UniProt
153	N-linked (GlcNAc...) asparagine	UniProt
186	N-linked (GlcNAc...) asparagine	UniProt
282	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 12 in total

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Pathway Name	Organism
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	Rattus norvegicus
IKK complex recruitment mediated by RIP1	Rattus norvegicus
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Rattus norvegicus
Ligand-dependent caspase activation	Rattus norvegicus
MyD88-independent TLR4 cascade	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	Rattus norvegicus
Regulation of TLR by endogenous ligand	Rattus norvegicus
TRAF6-mediated induction of TAK1 complex within TLR4 complex	Rattus norvegicus
TRIF-mediated programmed cell death	Rattus norvegicus