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Prostaglandin G/H synthase 1
Summary
- UniProt ID
- Q63921
- Gene Symbol
-
- Cox-1
- Cox1
- Ptgs1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Dioxygenase
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Heme
- Membrane
- Microsome
- Peroxidase
- Prostaglandin biosynthesis
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| nuclear envelope |
| cytoplasm |
| neuron projection |
| intracellular membrane-bounded organelle |
| endoplasmic reticulum membrane |
| photoreceptor outer segment |
Sequence
MSRRSLSLQFPLLLLLLLLPPPPVLLTDAGVPSPVNPCCYYPCQNQGVCVRFGLDHYQCDCTRTGYSGPNCTIPEIWTWLRSSLRPSPSFTHFLLTHGYWIWEFVNATFIREVLMRLVITVRSNLIPSPPTYNTAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDIHLLAQRLLLRREFIPGPQGTNVLFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDSLERQYHLRLFKDGKLKYQVLDGEVYPPSVEQASVLMRYPPGVPPEKQMAVGQEVFGLLPGLMLFSTIWLREHNRVCDLLKEEHPTWDDEQLFQTTRLILIGETIKIIIEEYVQHLSGYFLQLKFDPELLFRAQFQYRNRIALEFNHLYHWHPLMPDSFQVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQRAGRIGGGRNFDYHVLHVAEDVIKESREMRLQSFNEYRKRFGLKPYTSFQEFTGEKEMAAELEELYGDIDALEFYPGLMLEKCQPNSLFGESMIEMGAPFSLKGLLGNPICSPEYWKPSTFGGDVGFNIVNTASLKKLVCLNTKTCPYVSFRVPDYPGDDGSVFVRPSTEL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| COX reactions | Rattus norvegicus |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:1591 | renovascular hypertension | |
| DOID:8577 | ulcerative colitis |
