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Dopamine beta-hydroxylase
Summary
- UniProt ID
- Q64237
- Gene Symbol
-
- Dbh
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Catecholamine biosynthesis
- Copper
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Metal-binding
- Monooxygenase
- Phosphoprotein
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Vitamin C
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| axon |
| secretory granule membrane |
| terminal bouton |
| dendrite |
| transport vesicle membrane |
| neuronal cell body |
| secretory granule lumen |
| apical part of cell |
| varicosity |
| GO Term |
|---|
| L-ascorbic acid binding |
| dopamine beta-monooxygenase activity |
| copper ion binding |
Sequence
MQAHLSHQPCWSSLPSPSVREAASMYGTAVAIFLVILVAALRGSEPPESPFPYHIPLDPEGILELSWNVSYVQEIIHFQLQVQGLRAGVLFGMSDRGEMENADLIMLWTDGDRAYFADAWSDRKGQIHLDSQQDYQLLQAQRTRDGLSLLFKRPFVTCDPKDYVIEDDTVHLVYGILEEPFQSLEAINTSGLHTGLQRVQLLKSEVPTPSMPEDVQTMDIRAPDILIPDNETTYWCYITELPPRFPRHHIIMYEAIVTEGNEALVHHMEVFQCAAESEDFPQFNGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPKEAGVPFGGPGSSPFLRLEVHYHNPRKIQGRQDSSGIRLHYTATLRRYDAGIMELGLVYTPLMAIPPQETAFVLTGYCTDKCTQMALQDSGIHIFASQLHTHLTGRKVVTVLARDGQERKVVNRDNHYSPHFQEIRMLKKVVTVYPGDVLITSCTYNTENKTLATVGGFGILEEMCVNYVHYYPQTELELCKSAVDDGFLQKYFHMVNRFSSEEVCTCPQASVPQQFSSVPWNSFNRDMLKALYDYAPISMHCNKTSAVRFPGEWNLQPLPKITSTLEEPTPRCPIRQTQSPANPTVPITTEADAE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 68 | N-linked (GlcNAc...) asparagine |
|
||
| 188 | N-linked (GlcNAc...) asparagine |
|
||
| 476 | N-linked (GlcNAc...) asparagine | |||
| 570 | N-linked (GlcNAc...) asparagine |
G80920RR
G05724UK
G41247ZX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Catecholamine biosynthesis | Mus musculus |
