GlyCosmos Portal

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Sortilin

Summary

UniProt ID

Q6PHU5

Gene Symbol

Sort1

Gene ID

20661

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0005844

GlyConnect

Sortilin

GlyGen

Q6PHU5

PubChem

Q6PHU5

Re-Glyco

Q6PHU5

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cleavage on pair of basic residues
Developmental protein
Differentiation
Disulfide bond
Endocytosis
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Lysosome
Nucleus
Osteogenesis
Palmitate
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Transport

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
clathrin-coated pit
endosome membrane
trans-Golgi network transport vesicle
cerebellar climbing fiber to Purkinje cell synapse
plasma membrane
cytoplasmic vesicle membrane
nuclear membrane
early endosome
endoplasmic reticulum membrane
Golgi apparatus

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 18 in total

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GO Term
myotube differentiation
endosome transport via multivesicular body sorting pathway
plasma membrane to endosome transport
Golgi to lysosome transport
extrinsic apoptotic signaling pathway via death domain receptors
response to insulin
negative regulation of fat cell differentiation
neuropeptide signaling pathway
endosome to lysosome transport
protein targeting to lysosome

Displaying **all 5** entries
GO Term
nerve growth factor receptor activity
neurotensin receptor activity, non-G protein-coupled
enzyme binding
retromer complex binding
nerve growth factor binding

Annotation information from UniProt.

Sequence

MERPRGAADGLLRWPLGLLLLLQLLPPAAVGQDRLDAPPPPAPPLLRWAGPVGVSWGLRAAAPGGPVPRAGRWRRGAPAEDQDCGRLPDFIAKLTNNTHQHVFDDLSGSVSLSWVGDSTGVILVLTTFQVPLVIVSFGQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSRGGRVFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKNFGEKWEEIHKAVCLAKWGPNNIIFFTTHVNGSCKADLGALELWRTSDLGKTFKTIGVKIYSFGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANEDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSTLSEDNSIQSMITFDQGGRWEHLRKPENSKCDATAKNKNECSLHIHASYSISQKLNVPMAPLSEPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWAKMLEGPHYYTILDSGGIIVAIEHSNRPINVIKFSTDEGQCWQSYVFTQEPIYFTGLASEPGARSMNISIWGFTESFITRQWVSYTVDFKDILERNCEEDDYTTWLAHSTDPGDYKDGCILGYKEQFLRLRKSSVCQNGRDYVVAKQPSVCPCSLEDFLCDFGYFRPENASECVEQPELKGHELEFCLYGKEEHLTTNGYRKIPGDKCQGGMNPAREVKDLKKKCTSNFLNPTKQNSKSNSVPIILAIVGLMLVTVVAGVLIVKKYVCGGRFLVHRYSVLQQHAEADGVEALDSTSHAKSGYHDDSDEDLLE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	GlyTouCan ID	Source
96	N-linked (GlcNAc...) asparagine		UniProt GlyGen
160	N-linked (GlcNAc...) asparagine	G86182NS G64527OM G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
235			GlyGen
272	N-linked (GlcNAc...) asparagine	G05049YU	GlycoProtDB UniProt GlyGen
404	N-linked (GlcNAc...) asparagine	G83460ZZ G72398FA G70101JE	GlycoProtDB UniProt GlyGen GlyConnect
580	N-linked (GlcNAc...) asparagine	G64527OM G05724UK G92275SC	GlycoProtDB UniProt GlyGen GlyConnect
682	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen