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Apolipoprotein A-V

Summary

UniProt ID

Q6Q788

Gene Symbol

APOA5
RAP3
UNQ411/PRO773

Gene ID

116519

Organism

Homo sapiens (human)

External Links

GlyGen: Q6Q788
PubChem: Q6Q788
The Human Metabolome Database: HMDBP10986
Re-Glyco: Q6Q788

Annotation

Keyword

Chylomicron
Coiled coil
Disease variant
Endosome
Golgi apparatus
HDL
Lipid transport
Phosphoprotein
Reference proteome
Secreted
Signal
VLDL

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
extracellular vesicle
extracellular region
extracellular space
chylomicron
early endosome
late endosome
endoplasmic reticulum lumen
Golgi apparatus
very-low-density lipoprotein particle
high-density lipoprotein particle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 18 in total

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GO Term
lipid transport
tissue regeneration
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
triglyceride-rich lipoprotein particle remodeling
positive regulation of fatty acid biosynthetic process
positive regulation of lipid catabolic process
positive regulation of lipoprotein lipase activity
acylglycerol homeostasis
cholesterol metabolic process

Displaying entries **1 - 10** of 13 in total

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GO Term
heparin binding
phosphatidylcholine-sterol O-acyltransferase activator activity
lipoprotein lipase activator activity
phospholipid binding
lipid binding
enzyme binding
low-density lipoprotein particle receptor binding
cholesterol transfer activity
phosphatidylcholine binding
lipoprotein particle receptor binding

Annotation information from UniProt.

Sequence

MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGHSHLGDP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
74			G57321FI	GlyGen
80			G57321FI	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Assembly of active LPL and LIPC lipase complexes	Homo sapiens
Chylomicron remodeling	Homo sapiens
PPARA activates gene expression	Homo sapiens
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens

Disease

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0111421	familial apolipoprotein A5 deficiency	Alliance of Genome Resources
DOID:1171	hyperlipoproteinemia type V	Alliance of Genome Resources
DOID:1172	hyperlipoproteinemia type IV	Alliance of Genome Resources
DOID:3393	coronary artery disease	Alliance of Genome Resources
DOID:3526	cerebral infarction	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements