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Apolipoprotein A-V

Summary

UniProt ID

Q6Q788

Gene Symbol

APOA5
RAP3

Organism

Homo sapiens (human)

External Links

GlyGen: Q6Q788
PubChem: Q6Q788
The Human Metabolome Database: HMDBP10986

Annotation

Keyword

Chylomicron
Coiled coil
Disease variant
Endosome
Golgi apparatus
HDL
Lipid transport
Phosphoprotein
Reference proteome
Secreted
Signal
VLDL

Gene Ontology (GO)

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GO Term
positive regulation of lipid catabolic process
positive regulation of lipoprotein lipase activity
acylglycerol homeostasis
cholesterol metabolic process
cholesterol homeostasis
positive regulation of receptor-mediated endocytosis
triglyceride metabolic process
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
triglyceride catabolic process

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GO Term
extracellular region
extracellular space
Golgi apparatus
extracellular vesicle
early endosome
late endosome
endoplasmic reticulum lumen
very-low-density lipoprotein particle
high-density lipoprotein particle
chylomicron

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GO Term
enzyme activator activity
heparin binding
lipid binding
enzyme binding
low-density lipoprotein particle receptor binding
phosphatidylcholine-sterol O-acyltransferase activator activity
lipoprotein lipase activator activity
lipoprotein particle receptor binding
phosphatidylcholine binding
lipase activator activity

Annotation information from UniProt.

Sequence

MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGHSHLGDP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
74			G57321FI	GlyGen
80			G57321FI	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Assembly of active LPL and LIPC lipase complexes	Homo sapiens
Chylomicron remodeling	Homo sapiens
PPARA activates gene expression	Homo sapiens
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens