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GDNF family receptor alpha-like

Summary

UniProt ID

Q6UXV0

Gene Symbol

GFRAL
C6orf144

Organism

Homo sapiens (human)

External Links

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Glycoprotein
Hormone
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
response to metformin
nervous system development
reduction of food intake in response to dietary excess
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
stress-activated protein kinase signaling cascade
negative regulation of appetite

Displaying **all 6** entries
GO Term
plasma membrane
actin cytoskeleton
receptor complex
focal adhesion
nucleoplasm
external side of plasma membrane

Displaying **all 4** entries
GO Term
glial cell-derived neurotrophic factor receptor activity
signaling receptor activity
hormone activity
receptor tyrosine kinase binding

Annotation information from UniProt.

Sequence

MIVFIFLAMGLSLENEYTSQTNNCTYLREQCLRDANGCKHAWRVMEDACNDSDPGDPCKMRNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKLLGKKCINKSDNVKEDKFKWNLTTRSHHGFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQCQAAIRFFYQNIPFNIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQRVTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVLQVQCTCRTITQSEESLCKIFQHMLHRKSCFNYPTLSNVKGMALYTRKHANKITLTGFHSPFNGEVIYAAMCMTVTCGILLLVMVKLRTSRISSKARDPSSIQIPGEL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
23	N-linked (GlcNAc...) asparagine	UniProt
50	N-linked (GlcNAc...) asparagine	UniProt
62	N-linked (GlcNAc...) asparagine	UniProt
67	N-linked (GlcNAc...) asparagine	UniProt
103	N-linked (GlcNAc...) asparagine	UniProt
116	N-linked (GlcNAc...) asparagine	UniProt