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GDNF family receptor alpha-like

Summary

UniProt ID

Q6UXV0

Gene Symbol

GFRAL
C6orf144

Organism

Homo sapiens (human)

External Links

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Glycoprotein
Hormone
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
nervous system development
negative regulation of neuron apoptotic process
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
stress-activated protein kinase signaling cascade
negative regulation of appetite
glial cell-derived neurotrophic factor receptor signaling pathway
reduction of food intake in response to dietary excess
positive regulation of MAPK cascade
response to metformin

Displaying **all 6** entries
GO Term
focal adhesion
external side of plasma membrane
plasma membrane
actin cytoskeleton
receptor complex
nucleoplasm

Displaying **all 3** entries
GO Term
signaling receptor activity
glial cell-derived neurotrophic factor receptor activity
receptor tyrosine kinase binding

Annotation information from UniProt.

Sequence

MIVFIFLAMGLSLENEYTSQTNNCTYLREQCLRDANGCKHAWRVMEDACNDSDPGDPCKMRNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKLLGKKCINKSDNVKEDKFKWNLTTRSHHGFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQCQAAIRFFYQNIPFNIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQRVTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVLQVQCTCRTITQSEESLCKIFQHMLHRKSCFNYPTLSNVKGMALYTRKHANKITLTGFHSPFNGEVIYAAMCMTVTCGILLLVMVKLRTSRISSKARDPSSIQIPGEL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
23	N-linked (GlcNAc...) asparagine	UniProt
50	N-linked (GlcNAc...) asparagine	UniProt
62	N-linked (GlcNAc...) asparagine	UniProt
67	N-linked (GlcNAc...) asparagine	UniProt
103	N-linked (GlcNAc...) asparagine	UniProt
116	N-linked (GlcNAc...) asparagine	UniProt