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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glypican-3
Summary
- UniProt ID
- Q6V9Y8
- Gene Symbol
-
- gpc3
- Organism
- Danio rerio (zebrafish)
External Links
- PubChem
- Q6V9Y8
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- GPI-anchor
- Heparan sulfate
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of protein localization to membrane |
| GO Term |
|---|
| collagen-containing extracellular matrix |
| cell surface |
| side of membrane |
| plasma membrane |
Sequence
MMPGLKLYGALILCVLVLPFSRPSSQVLDCREVRSSFQFLYPGMKWTPETPVSGSDLQVCQPKGLTCCSRKMEERYLLIAKQNMESSLQATSAQLKGLIIQNAALFQEAFDMVLRLGRNSTLMVLREEFPGLGAGASGAVTQLFLDMSLYILGSDANVNDMVSTFFSRLFPLTYRRLLGNGAVAGISEECLRGAWKGSSAYGSFPKMMMTRLSRSLLATRVFLQALNLGIEVVNTTQHLRAGRDCGRSLLKLWYCPHCQSLLEARPCRPLCVSTMGACLGGTTEVQPHWRAYVDELGSLAAAMKGEQDIEAVVLRLHVIIRQALKQAVASKSKVSAQVSGMCVHAPPRVSRAVPVSAEHTSASTVNHNRPPMNFDPDETLFGRRREFISGLRGFSQFYSGLGEALCSKEPTSLNSSLCWNGQEMTDKFPGPGLKRVHPHGSESKQKTPEPVISQIIDKLKHINQLLRMVTLPEKRWRARQGGGGARRNPSGPGQTDEDEEGLESGDCDDEDECTGVSGLGPPPRRKRLRIFADLADNLAIDDLTLHELLLTPRLATDAHGGSSIPGAAHVPTAAFIFTITIIIFITLGLQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 119 | N-linked (GlcNAc...) asparagine |
|
||
| 234 | N-linked (GlcNAc...) asparagine |
|
||
| 414 | N-linked (GlcNAc...) asparagine |
|
||
| 504 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 517 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Danio rerio |
| HS-GAG biosynthesis | Danio rerio |
| HS-GAG degradation | Danio rerio |
