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MIRAGE
Hemojuvelin

Summary
UniProt ID
Q6ZVN8
Gene Symbol
  • HFE2
  • HJV
  • RGMC
Gene ID
148738
Organism
Homo sapiens (human)
GlyGen
Q6ZVN8
PubChem
Q6ZVN8
The Human Metabolome Database
HMDBP08689
Re-Glyco
Q6ZVN8
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Autocatalytic cleavage
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • GPI-anchor
  • Phosphoprotein
  • Reference proteome
  • Signal
Gene Ontology (GO)
Displaying all 7 entries
GO Term
BMP receptor complex
HFE-transferrin receptor complex
extracellular space
plasma membrane
plasma membrane protein complex
cell surface
side of membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MGEPGQSPSPRSSHGSPPTLSTLTLLLLLCGHAHSQCKILRCNAEYVSSTLSLRGGGSSGALRGGGGGGRGGGVGSGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPPRGPALPGAGSGLPAPDPCDYEGRFSRLHGRPPGFLHCASFGDPHVRSFHHHFHTCRVQGAWPLLDNDFLFVQATSSPMALGANATATRKLTIIFKNMQECIDQKVYQAEVDNLPVAFEDGSINGGDRPGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPSDAGVPLSSATLLAPLLSGLFVLWLCIQ
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
118 N-linked (GlcNAc...) asparagine
125
213 N-linked (GlcNAc...) asparagine
372 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Netrin-1 signaling Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0111027 hemochromatosis type 2A
DOID:2352 hemochromatosis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025