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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Carbohydrate sulfotransferase 3
Summary
- UniProt ID
- Q7LGC8
- Gene Symbol
-
- CHST3
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0012311
- GlyGen
- Q7LGC8
- PubChem
- Q7LGC8
- The Human Metabolome Database
- HMDBP00287
Annotation
- Keyword
-
- Carbohydrate metabolism
- Disease variant
- Glycoprotein
- Golgi apparatus
- Reference proteome
- Signal-anchor
- Transferase
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| trans-Golgi network |
| GO Term |
|---|
| proteoglycan sulfotransferase activity |
| N-acetylglucosamine 6-O-sulfotransferase activity |
| chondroitin 6-sulfotransferase activity |
Sequence
MEKGLTLPQDCRDFVHSLKMRSKYALFLVFVVIVFVFIEKENKIISRVSDKLKQIPQALADANSTDPALILAENASLLSLSELDSAFSQLQSRLRNLSLQLGVEPAMEAAGEEEEEQRKEEEPPRPAVAGPRRHVLLMATTRTGSSFVGEFFNQQGNIFYLFEPLWHIERTVSFEPGGANAAGSALVYRDVLKQLFLCDLYVLEHFITPLPEDHLTQFMFRRGSSRSLCEDPVCTPFVKKVFEKYHCKNRRCGPLNVTLAAEACRRKEHMALKAVRIRQLEFLQPLAEDPRLDLRVIQLVRDPRAVLASRMVAFAGKYKTWKKWLDDEGQDGLREEEVQRLRGNCESIRLSAELGLRQPAWLRGRYMLVRYEDVARGPLQKAREMYRFAGIPLTPQVEDWIQKNTQAAHDGSGIYSTQKNSSEQFEKWRFSMPFKLAQVVQAACGPAMRLFGYKLARDAAALTNRSVSLLEERGTFWVT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 63 | N-linked (GlcNAc...) asparagine |
|
||
| 74 | N-linked (GlcNAc...) asparagine |
|
||
| 96 | N-linked (GlcNAc...) asparagine |
|
||
| 256 | N-linked (GlcNAc...) asparagine | |||
| 420 | N-linked (GlcNAc...) asparagine | |||
| 464 | N-linked (GlcNAc...) asparagine |
G83460ZZ
G80920RR
G62765YT
G41247ZX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Chondroitin sulfate biosynthesis | Homo sapiens |
| Defective CHST3 causes SEDCJD | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080362 | X-linked spondyloepiphyseal dysplasia tarda | |
| DOID:0080365 | endometrial hyperplasia | |
| DOID:0080575 | Larsen-like syndrome B3GAT3 type | |
| DOID:0090004 | progressive pseudorheumatoid arthropathy of childhood | |
| DOID:0090005 | Schwartz-Jampel syndrome 1 | |
| DOID:0090032 | Silverman-Handmaker type dyssegmental dysplasia | |
| DOID:0090091 | hypogonadotropic hypogonadism 23 with or without anosmia | |
| DOID:0110106 | atrial heart septal defect 1 | |
| DOID:0110107 | atrial heart septal defect 2 | |
| DOID:0110108 | atrial heart septal defect 3 |
