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Broad substrate specificity ATP-binding cassette transporter ABCG2

Summary

UniProt ID

Q80W57

Gene Symbol

Abcg2
Bcrp1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q80W57

Annotation

Keyword

ATP-binding
Cell membrane
Disulfide bond
Glycoprotein
Lipid transport
Mitochondrion
Phosphoprotein
Reference proteome
Translocase
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 25 in total

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GO Term
glucuronoside metabolic process
protein-containing complex assembly
export across plasma membrane
xenobiotic detoxification by transmembrane export across the plasma membrane
cellular response to dexamethasone stimulus
response to iron ion
riboflavin transport
transepithelial transport
cellular response to estradiol stimulus
response to alcohol

Displaying **all 6** entries
GO Term
external side of apical plasma membrane
apical plasma membrane
plasma membrane
mitochondrial membrane
membrane raft
brush border membrane

Displaying entries **1 - 10** of 14 in total

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GO Term
efflux transmembrane transporter activity
riboflavin transmembrane transporter activity
xenobiotic transmembrane transporter activity
organic anion transmembrane transporter activity
urate transmembrane transporter activity
biotin transmembrane transporter activity
amide transmembrane transporter activity
ATP binding
cytoskeletal protein binding
ABC-type xenobiotic transporter activity

Annotation information from UniProt.

Sequence

MSSSNDHVLVPMSQRNKNGLPGMSSRGARTLAEGDVLSFHHITYRVKVKSGFLVRKTAEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPRGLSGDVLINGAPQPANFKCSSGYVVQDDVVMGTLTVRENLQFSAALRLPKAMKTHEKNERINTIIKELGLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKALEYFASAGYHCEPYNNPADFFLDVINGDSSAVMLNRGEQDHEANKTEEPSKREKPIIENLAEFYINSTIYGETKAELDQLPVAQKKKGSSAFREPVYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGALYFGLKNDPTGMQNRAGVFFFLTTNQCFTSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKLVSDLLPMRFLPSVIYTCILYFMLGLKRTVEAFFIMMFTLIMVAYTASSMALAIAAGQSVVSVATLLMTISFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQHNEFLGQEFCPGLNVTMNSTCVNSYTICTGNDYLINQGIDLSPWGLWRNHVALACMIIIFLTIAYLKLLFLKKYS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
596	N-linked (GlcNAc...) asparagine			UniProt
600	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
APAP ADME	Rattus norvegicus
Ciprofloxacin ADME	Rattus norvegicus
Heme biosynthesis	Rattus norvegicus
Heme degradation	Rattus norvegicus
Iron uptake and transport	Rattus norvegicus
Sphingolipid de novo biosynthesis	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements