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ER degradation-enhancing alpha-mannosidase-like protein 2

Summary

UniProt ID

Q8BJT9

Gene Symbol

Edem2

Organism

Mus musculus (house mouse)

External Links

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Reference proteome
Signal
Unfolded protein response

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
response to unfolded protein
mannoprotein catabolic process
positive regulation of retrograde protein transport, ER to cytosol
carbohydrate metabolic process
ERAD pathway

Displaying **all 3** entries
GO Term
endoplasmic reticulum
endoplasmic reticulum lumen
membrane

Displaying **all 2** entries
GO Term
calcium ion binding
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

Annotation information from UniProt.

Sequence

MPFRLLIPLGLVCVLLPLHHGAPGPDGTAPDPAHYRERVKAMFYHAYDSYLENAFPYDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNTSEFQRVVEVLQDNVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFLEYNKAIRNYTHFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFHPNNFIHNNGSTFDSVMTPHGECILGAGGYIFNTEAHPIDPAALHCCRRLKEEQWEVEDLIKEFYSLKQSRPKRAQRKTVRSGPWEPQSGPATLSSPANQPREKQPAQQRTPLLSCPSQPFTSKLALLGQVFLDSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
90	N-linked (GlcNAc...) asparagine	UniProt
112	N-linked (GlcNAc...) asparagine	UniProt
289	N-linked (GlcNAc...) asparagine	UniProt
450	N-linked (GlcNAc...) asparagine	UniProt