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Protein argonaute-2

Summary

UniProt ID

Q8CJG0

Gene Symbol

Ago2
Eif2c2
Kiaa4215

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8CJG0
PubChem: Q8CJG0
The O-GlcNAc Database: Q8CJG0

Annotation

Keyword

Cytoplasm
Developmental protein
Differentiation
Endonuclease
Hydroxylation
Magnesium
Manganese
Metal-binding
Nitration
Nucleus
Phosphoprotein
RNA-binding
RNA-mediated gene silencing
Reference proteome
Repressor
Ribonucleoprotein
Transcription regulation
Translation regulation
Ubl conjugation

Gene Ontology (GO)

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GO Term
RNA secondary structure unwinding
miRNA metabolic process
siRNA processing
regulation of mRNA stability
miRNA-mediated gene silencing by inhibition of translation
miRNA-mediated gene silencing by mRNA destabilization
RISC complex assembly
siRNA-mediated gene silencing by mRNA destabilization
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
positive regulation of post-transcriptional gene silencing by RNA

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GO Term
Golgi apparatus
membrane
dendrite
extracellular exosome
ribonucleoprotein complex
RISC complex
P granule
mitochondrion
cytosol
P-body

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GO Term
RNA binding
siRNA binding
miRNA binding
endoribonuclease activity, cleaving siRNA-paired mRNA
endoribonuclease activity, cleaving miRNA-paired mRNA
mRNA cap binding
RISC complex binding
metal ion binding
Hsp90 protein binding
Hsp70 protein binding

Annotation information from UniProt.

Sequence

MYSGAGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
360			G54010QB	GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
MicroRNA (miRNA) biogenesis	Mus musculus
Post-transcriptional silencing by small RNAs	Mus musculus
Small interfering RNA (siRNA) biogenesis	Mus musculus
Transcriptional regulation by small RNAs	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements