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Thyroid peroxidase

Summary

UniProt ID

Q8HYB7

Gene Symbol

TPO

Organism

Canis lupus familiaris (dog)

External Links

PubChem: Q8HYB7

Annotation

Keyword

Calcium
Disulfide bond
EGF-like domain
Glycoprotein
Heme
Hydrogen peroxide
Reference proteome
Signal
Sushi
Thyroid hormones biosynthesis
Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
hydrogen peroxide catabolic process
thyroid hormone generation
response to oxidative stress
hormone biosynthetic process

Displaying **all 2** entries
GO Term
extracellular space
membrane

Displaying **all 4** entries
GO Term
calcium ion binding
heme binding
peroxidase activity
iodide peroxidase activity

Annotation information from UniProt.

Sequence

MVGLVPAGSAWGGRALAVLGVTLLVALARGLLPFFLGGRDLLWGQSGEASVLGVVEESRRVVDGAIQHTVRRDLSKRGLPSPSQLLSFSKLPEPTSRAVSRAAEIMEASVQAVRTRVYGKLGRSWPLTDTLPEAVLDTIANASGCRPHMLPPRCPDTCLARKYRLITGACNNRDHPRWGASNTALARWLPPAYEDGISEPRGWNPHVLYSGFPLPPVREVTRQVIRVPNEAVTEDDQYSDLLTVWGQYIDHDVAFTPQSASGAAFGAGADCQLTCENRSPCFPIQLPPDASGPACLPFSRSSAACGTGIQGAFFGNLSSANPRQQMNGLTSFLDASTVYGSSPALEKQLRNWTSAEGLLRVNTRHWDAGRAHLPFMRPPAPLACVPEPGTRGTAGAPCFLAGDSRASEVPTLAALHTLWLREHNRLASALKALNAHWSADTAYQEARKVVGALHQIITLRDYVPKVLGPEAFQQHVGPYEGYDPTMDPTVSNVFSTAAFRLGHATVHPLVRRLDARFQEHPGLPPLGLQDAFFPWRLLKEGGLDPLLRGLLASPAKLPVQEQLMNEELTERLFVLGSSGSLDLASINLQRGRDHGLPGYNAWREFCGLGRLHTRAELRSAVANATLAGRIMDLYGHPDNIDVWLGGLAEPLLPRARTGPLFACLIGRQMKALRDGDRFWWESSGVFTDEQRRELARHSLSRVICDNTGLPSVPADAFQVSRFPQDFEPCENIPGLNLDVWREALPQGDACGLPDSLDNGDVVLCGEAGRRVLVFSCRHGFKLQGPEQVACSPRGGAVRAPVCRDINECEDASHPPCHGSARCRNTKGGFRCECTDPAVLGEDGTTCVDSGRLPKASLVSIALGIVLVVGLAGLTWTLVCRWAHAGRKASLSIAELGGRGAPPPGRGAGQDGASGSLVPPLGPQGRTRAVDPTSSRSHVAQGSPA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
141	N-linked (GlcNAc...) asparagine	UniProt
316	N-linked (GlcNAc...) asparagine	UniProt
351	N-linked (GlcNAc...) asparagine	UniProt
623	N-linked (GlcNAc...) asparagine	UniProt