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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
5'-3' exonuclease PLD3
Summary
- UniProt ID
- Q8IV08
- Gene Symbol
-
- PLD3
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- Q8IV08
- PubChem
- Q8IV08
- The Human Metabolome Database
- HMDBP07291
- The O-GlcNAc Database
- Q8IV08
Annotation
- Keyword
-
- 3D-structure
- Disease variant
- Endoplasmic reticulum
- Endosome
- Exonuclease
- Glycoprotein
- Golgi apparatus
- Immunity
- Inflammatory response
- Lysosome
- Reference proteome
- Repeat
- Signal-anchor
- Spinocerebellar ataxia
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| immune system process |
| inflammatory response |
| myotube differentiation |
| regulation of cytokine production involved in inflammatory response |
| GO Term |
|---|
| Golgi membrane |
| endoplasmic reticulum membrane |
| lysosomal lumen |
| lysosomal membrane |
| extracellular exosome |
| early endosome membrane |
| late endosome membrane |
| GO Term |
|---|
| phospholipase D activity |
| single-stranded DNA 5'-3' DNA exonuclease activity |
Sequence
MKPKLMYQELKVPAEEPANELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRPAPCYDPCEAVLVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLRQLQTLAPKGVNVRIAVSKPSGPQPQADLQALLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYVAVMNYLPTLEFSHPHRFWPAIDDGLRRATYERGVKVRLLISCWGHSEPSMRAFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERATYIGTSNWSGNYFTETAGTSLLVTQNGRGGLRSQLEAIFLRDWDSPYSHDLDTSADSVGNACRLL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 97 | N-linked (GlcNAc...) asparagine |
|
||
| 132 | N-linked (GlcNAc...) asparagine |
|
||
| 236 |
|
|||
| 284 |
|
|||
| 387 |
|
|||
| 432 |
|
|||
|
|
G06247RL
G45395BF
G00912UN
G48414YA
G70101JE
G80920RR
G47950XN
G11870QZ
G47644PP
G82119TF
G55383ZG
G85269DF
G72291OX
G95865ZB
G92050GC
G74724QE
G92275SC
G14669DU
G28681TP
G14260UH
G83633GK
G64527OM
G05724UK
G39188ZX
G06110VR
G70232NH
G57776ZS
G29545VG
G79666IR
G43223CG
G27058EU
G83460ZZ
G62765YT
G31852PQ
G26330YA
G40574BA
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Role of phospholipids in phagocytosis | Homo sapiens |
| Synthesis of PG | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080288 | spinocerebellar ataxia 46 | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0110035 | Alzheimer's disease 2 | |
| DOID:0110037 | Alzheimer's disease 5 | |
| DOID:0110038 | Alzheimer's disease 6 | |
| DOID:0110039 | Alzheimer's disease 7 | |
| DOID:0110041 | Alzheimer's disease 8 | |
| DOID:0110043 | Alzheimer's disease 10 | |
| DOID:0110044 | Alzheimer's disease 11 | |
| DOID:0110045 | Alzheimer's disease 12 |
