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Serpin A12

Summary

UniProt ID

Q8IW75

Gene Symbol

SERPINA12

Organism

Homo sapiens (human)

External Links

GlyGen: Q8IW75

Annotation

Keyword

3D-structure
Glycoprotein
Reference proteome
Secreted
Serine protease inhibitor
Signal

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
gluconeogenesis
lipid biosynthetic process
negative regulation of gluconeogenesis
negative regulation of lipid biosynthetic process
regulation of cholesterol metabolic process
regulation of triglyceride metabolic process
phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of insulin receptor signaling pathway
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

Displaying **all 2** entries
GO Term
extracellular space
plasma membrane

Displaying **all 2** entries
GO Term
molecular function inhibitor activity
serine-type endopeptidase inhibitor activity

Annotation information from UniProt.

Sequence

MNPTLGLAIFLAVLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	Source
221	N-linked (GlcNAc...) (complex) asparagine	28668641	UniProt GlyGen
233	N-linked (GlcNAc...) (complex) asparagine	28668641	UniProt GlyGen
267	N-linked (GlcNAc...) (high mannose) asparagine	28668641	UniProt GlyGen