GlyCosmos Portal

Submissions

Serpin A12

Summary

UniProt ID

Q8IW75

Gene Symbol

SERPINA12

Organism

Homo sapiens (human)

External Links

GlyGen: Q8IW75
The O-GlcNAc Database: Q8IW75

Annotation

Keyword

3D-structure
Glycoprotein
Reference proteome
Secreted
Serine protease inhibitor
Signal

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
gluconeogenesis
lipid biosynthetic process
regulation of triglyceride metabolic process
negative regulation of gluconeogenesis
positive regulation of insulin receptor signaling pathway
negative regulation of lipid biosynthetic process
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
phosphatidylinositol 3-kinase/protein kinase B signal transduction
regulation of cholesterol metabolic process

Displaying **all 2** entries
GO Term
extracellular space
plasma membrane

Displaying **all 2** entries
GO Term
serine-type endopeptidase inhibitor activity
molecular function inhibitor activity

Annotation information from UniProt.

Sequence

MNPTLGLAIFLAVLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
221	N-linked (GlcNAc...) (complex) asparagine	28668641		UniProt GlyGen
233	N-linked (GlcNAc...) (complex) asparagine	28668641		UniProt GlyGen
267	N-linked (GlcNAc...) (high mannose) asparagine	28668641		UniProt GlyGen
			G49108TO	GlyGen The O-GlcNAc Database