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Volume-regulated anion channel subunit LRRC8A
Summary
- UniProt ID
- Q8IWT6
- Gene Symbol
-
- LRRC8A
- KIAA1437
- LRRC8
- SWELL1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cell membrane
- Chromosomal rearrangement
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Ion channel
- Leucine-rich repeat
- Lysosome
- Phosphoprotein
- Reference proteome
- Repeat
- Spermatogenesis
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| lysosomal membrane |
| plasma membrane |
| membrane |
| monoatomic ion channel complex |
| cell surface |
| GO Term |
|---|
| cyclic-GMP-AMP transmembrane transporter activity |
| identical protein binding |
| volume-sensitive anion channel activity |
Sequence
MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWVTKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHWFAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEESDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQAKALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIESLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREESSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRLTKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFNTLPPEVKERLWRADKEQA
Glycosylation Sites
G65184UU
G62765YT
G31852PQ
G41247ZX
G02815KT
G34029GR
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Miscellaneous transport and binding events | Homo sapiens |
