Voltage-dependent calcium channel subunit alpha-2/delta-3

Summary
UniProt ID
Q8IZS8
Gene Symbol
  • CACNA2D3
Organism
Homo sapiens (human)
External Links
PubChem
Q8IZS8
The Human Metabolome Database
HMDBP07486
Annotation
Keyword
  • Alternative splicing
  • Calcium channel
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Phosphoprotein
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Voltage-gated channel
Gene Ontology (GO)
Displaying 1 entry
GO Term
voltage-gated calcium channel complex
Sequence
MAGPGSPRRASRGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGPVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGAHGLLDPYNAFLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQKLKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCESVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSLQAQTVLLLLPLLLMLFSR
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
166 N-linked (GlcNAc...) asparagine
309 N-linked (GlcNAc...) asparagine
553 N-linked (GlcNAc...) asparagine
632 N-linked (GlcNAc...) asparagine
793 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Presynaptic depolarization and calcium channel opening Homo sapiens
Disease
Displaying entries 1 - 10 of 28 in total
DO ID Disease Name Source
DOID:0050742 nicotine dependence
DOID:10283 prostate cancer
DOID:10286 prostate carcinoma
DOID:10534 stomach cancer
DOID:11252 microcytic anemia
DOID:11759 hypochromic anemia
DOID:13121 deficiency anemia
DOID:1380 endometrial cancer
DOID:1612 breast cancer
DOID:162 cancer

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024