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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement component C8 alpha chain
Summary
- UniProt ID
- Q8K182
- Gene Symbol
-
- C8a
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- Complement alternate pathway
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Membrane attack complex
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane beta strand
- Gene Ontology (GO)
| GO Term |
|---|
| membrane attack complex |
| extracellular region |
| extracellular space |
| plasma membrane |
| GO Term |
|---|
| protein-containing complex binding |
| complement binding |
Sequence
MFVVAFFGLSLVAWHPGVTAQEKVNQRVTRAVTPQAVSCQLSDWYKWTDCFPCQDKKYRYRSLLQPSKFGGTICSGDIWDEASCDSPTPCLRQAQCGQDFQCRETGRCLKRHLVCNGDNDCLDGSDESDCEDVRVTEDDCHQYEPIPGSERAALGYNILTQEEAQSVYDAKYYGGQCETVYNGDWRKLRYDPTCERLYYGEDEKYFRKPYNFLKYHFEALADTSISSEFYDDANDLFFHIKNGKSHSAGVTVGVAPVKSPVSIEVTGSGSKASSFLNKLNKYNEKRYGFMRVSTKIQTAQFKMRRNNIVLDEGMLQSLMELPEQFNYGMYAKFINDYGTHYITSGTMGGIYEYVMVLDKEKMKTEGTTVDEVQKCIGGGIGIGIKDSTIEGVGISGEFCENSGDGDRDIRKKITGVEDIISRVQGGSSVWGSVLTHNSSAITYQSWGRSLKYNPVVIDFEMQPIYQLLRHTNLGPLETKRQNLRRALDQYLMEFNACRCGPCFNNGEPILDGTNCRCQCSMGRQGLACERTVIEGLKDFKAAGHWSCWSSWSECRGGSQERRRQCNNPPPKNGGTPCLGRNLQTQAC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 44 | C-linked (Man) tryptophan |
|
||
| 437 | N-linked (GlcNAc...) asparagine |
|
||
| 545 | C-linked (Man) tryptophan |
|
||
| 548 | C-linked (Man) tryptophan |
|
||
| 551 | C-linked (Man) tryptophan |
|
||
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of Complement cascade | Mus musculus |
| Terminal pathway of complement | Mus musculus |
