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N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase

Summary

UniProt ID

Q8N0V5

Gene Symbol

GCNT2
GCNT5
II
NACGT1

Organism

Homo sapiens (human)

External Links

GlycoProtDB: GPDB0012385
GlyGen: Q8N0V5
PubChem: Q8N0V5
The Human Metabolome Database: HMDBP11751

Annotation

Keyword

Alternative splicing
Cataract
Disease variant
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transmembrane helix

Gene Ontology (GO)

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GO Term
glycosaminoglycan biosynthetic process
multicellular organism development
positive regulation of cell population proliferation
post-transcriptional regulation of gene expression
positive regulation of cell migration
positive regulation of epithelial to mesenchymal transition
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
protein glycosylation
transforming growth factor beta receptor signaling pathway
negative regulation of cell-substrate adhesion

Displaying **all 3** entries
GO Term
Golgi membrane
Golgi apparatus
membrane

Displaying **all 2** entries
GO Term
acetylglucosaminyltransferase activity
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity

Annotation information from UniProt.

Sequence

MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYPTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMPQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVASEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHKNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHFWVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNSPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
41	N-linked (GlcNAc...) asparagine		G62765YT	GlycoProtDB UniProt GlyGen
214			G83460ZZ	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Disease

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DO ID	Disease Name	Source
DOID:0080144	childhood acute lymphocytic leukemia	DisGeNET
DOID:0080199	colorectal carcinoma	DisGeNET
DOID:0110227	cataract 32 multiple types	DisGeNET
DOID:0110228	cataract 8 multiple types	DisGeNET
DOID:0110229	cataract 6 multiple types	DisGeNET
DOID:0110230	cataract 34 multiple types	DisGeNET
DOID:0110231	cataract 1 multiple types	DisGeNET
DOID:0110232	cataract 29	DisGeNET
DOID:0110233	cataract 27	DisGeNET
DOID:0110234	cataract 4 multiple types	DisGeNET

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements