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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glypican-2
Summary
- UniProt ID
- Q8N158
- Gene Symbol
-
- GPC2
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q8N158
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- GPI-anchor
- Heparan sulfate
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| lysosomal lumen |
| endoplasmic reticulum |
| Golgi lumen |
| cell surface |
| side of membrane |
| extracellular region |
| plasma membrane |
| synapse |
| collagen-containing extracellular matrix |
Sequence
MSALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLRVCPQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHPQYSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEALKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRGLEPDWGNYLDGLLILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAPPPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAADASLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATARMKTAALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGGGGSARYNQGRSRSGGASIGFHTQTILILSLSALALLGPR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 55 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 92 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 155 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 500 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 502 | O-linked (Xyl...) (heparan sulfate) serine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Homo sapiens |
| Attachment and Entry | Homo sapiens |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | Homo sapiens |
| Defective B3GAT3 causes JDSSDHD | Homo sapiens |
| Defective B4GALT7 causes EDS, progeroid type | Homo sapiens |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | Homo sapiens |
| Defective EXT2 causes exostoses 2 | Homo sapiens |
| HS-GAG biosynthesis | Homo sapiens |
| HS-GAG degradation | Homo sapiens |
| RSV-host interactions | Homo sapiens |
