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MIRAGE
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
Summary
- UniProt ID
- Q8N5C8
- Gene Symbol
-
- MAP3K7IP3
- TAB3
- Gene ID
- 257397
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Coiled coil
- Isopeptide bond
- Methylation
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| endoplasmic reticulum |
| cytosol |
| endosome membrane |
| extracellular exosome |
| GO Term |
|---|
| zinc ion binding |
| ubiquitin binding |
| molecular adaptor activity |
| K63-linked polyubiquitin modification-dependent protein binding |
Sequence
MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYMEYHSPDDNRMNRNRLLHINLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPRNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQSRGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKVQADIHDTQAAAADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPALNRCEQCEMPRYT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 235 |
|
|||
| 238 |
|
|||
| 398 |
|
|||
| 404 |
|
|||
| 408 |
|
|||
| 411 |
|
|||
| 440 |
|
|
||
| 667 |
|
|||
| 672 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ALPK1 signaling pathway | Homo sapiens |
| CLEC7A (Dectin-1) signaling | Homo sapiens |
| FCERI mediated NF-kB activation | Homo sapiens |
| IRAK2 mediated activation of TAK1 complex | Homo sapiens |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | Homo sapiens |
| Interleukin-1 signaling | Homo sapiens |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | Homo sapiens |
| NOD1/2 Signaling Pathway | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| TAK1-dependent IKK and NF-kappa-B activation | Homo sapiens |
