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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mixed lineage kinase domain-like protein
Summary
- UniProt ID
- Q8NB16
- Gene Symbol
-
- MLKL
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q8NB16
- PubChem
- Q8NB16
- The Human Metabolome Database
- HMDBP09462
- The O-GlcNAc Database
- Q8NB16
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell membrane
- Coiled coil
- Cytoplasm
- Necrosis
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| plasma membrane |
| cell junction |
| cytosol |
| GO Term |
|---|
| protein-containing complex binding |
| protein kinase binding |
| identical protein binding |
| ATP binding |
Sequence
MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTTAMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQRMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQYLPPKCMQEIPQEQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSIAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKTQTSMSLGTTREKTDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFSK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 253 |
|
|||
| 259 |
|
|||
| 357 |
|
|||
| 358 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Microbial modulation of RIPK1-mediated regulated necrosis | Homo sapiens |
| RIPK1-mediated regulated necrosis | Homo sapiens |
| Regulation of necroptotic cell death | Homo sapiens |
