GlyCosmos Portal

Submissions

IQ motif and SEC7 domain-containing protein 1

Summary

UniProt ID

Q8R0S2

Gene Symbol

Iqsec1
Kiaa0763

Gene ID

232227

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8R0S2
RaftProt: Q8R0S2
O-GlcNAcAtlas: Q8R0S2
Re-Glyco: Q8R0S2

Annotation

Keyword

Alternative splicing
Coiled coil
Cytoplasm
Cytoplasmic vesicle
Guanine-nucleotide releasing factor
Lipid-binding
Nucleus
Phosphoprotein
Reference proteome
Synapse

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
Schaffer collateral - CA1 synapse
glutamatergic synapse
nucleus
synaptic vesicle
postsynaptic density, intracellular component

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 6** entries
GO Term
positive regulation of focal adhesion disassembly
postsynaptic modulation of chemical synaptic transmission
positive regulation of keratinocyte migration
dendritic spine development
regulation of ARF protein signal transduction
regulation of postsynaptic neurotransmitter receptor internalization

Displaying **all 3** entries
GO Term
guanyl-nucleotide exchange factor activity
lipid binding
protein kinase binding

Annotation information from UniProt.

Sequence

MWCLHCNSERTQSLLELELDSGVEGEAPSSETGTSLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGPGPQQRTRRPRLQHSTSVLRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDPALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASDTARARDTEPKPGLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSDRSDRSSLKRQSAYERSLGGQQGSPKHGPHGGPPKGLPREEPELRPRPPRPLESHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVEFQPFQPPQPPVLCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites